Terrence L. Smalley, Ph.D., leads the chemistry team within Southern Research’s Drug Discovery division in oncology, neuroscience, infectious diseases, and metabolic diseases therapeutic areas. He has over 20 years of experience as a chemist in the pharmaceutical industry.
Prior to joining Southern Research, Smalley worked with GlaxoSmithKline, a leading pharmaceutical company. At GlaxoSmithKline, he gained extensive project leadership experience, including supervision of groups of chemists, medicinal chemistry, and synthetic organic chemists. Smalley plays a key role in hit identification from high-throughput screening (HTS), hit-to-lead (H2L) chemistry, design/prioritization of novel chemical targets, structure based drug design (SBDD), and lead optimization chemistry. Additionally, he is accustomed to working with chemists, designing novel synthetic organic pathways towards targets of interest, and decision-making regarding advancement of compounds to animal studies and beyond.
Smalley received his Bachelor of Science in chemistry from West Liberty State College and his Master of Science in organic chemistry from Wake Forest University. He then received his doctorate in organic chemistry from the University of Rochester.