Live-Attenuated Vaccine Development & Testing

Live-attenuated vaccines are a type of vaccine that uses a weakened form of a disease-causingvirus or bacteria. This weakened form of the virus or bacteria is still able to produce an immune response, but it is not able to cause disease in healthy people. Live-attenuated vaccines are safe, effective, and long-lasting, and they have been used to protect people from a variety of diseases, including Smallpox/Monkeypox, Measles, Mumps, Rubella, Polio, Yellow Fever, and Typhoid.


Accelerate Your Vaccine Development with Southern Research

Southern Research is a leading contract research organization (CRO) that specializes in the preclinical development of live-attenuated vaccines. We have a team of experienced scientists and researchers who are experts in all aspects of live-attenuated vaccine development, including:

  • Virus attenuation, propagation, and purification of live-attenuated vaccine candidates
  • In vitro and in vivo testing of live-attenuated vaccine candidates
  • Assessment of the safety and efficacy of live-attenuated vaccine candidates in relevant animals models
  • Assistance and consulting on the development and scale-up of a manufacturing process for live-attenuated vaccine candidates

We offer a wide range of preclinical live-attenuated vaccine development services, including:

  • Feasibility studies: We can help you assess the feasibility of developing a live-attenuated vaccine for your target disease.
  • Lead optimization: We can help you optimize your live-attenuated vaccine candidate to improve its safety and efficacy.
  • Preclinical testing: We can conduct all of the necessary preclinical testing to evaluate thesafety and efficacy of your live-attenuated vaccine candidate in relevant animal models.
  •  Manufacturing development: We can help you develop a robust manufacturing process for yourviral vector vaccine candidate so that it can be produced at scale for clinical trials.

If you are developing a live-attenuated vaccine candidate, we encourage you to contact us to learn more about how we can help you accelerate your vaccine development.