Bini Mathew, Ph.D.

Research Chemist

P: 205-581-2827

Dr. Mathew received her doctorate in organic chemistry from Mahatma Gandhi University by working at the National Institute for Interdisciplinary Science & Technology, a premier research institute under the Council of Scientific and Industrial Research (CSIR) of Ministry of Science and Technology, Government of India. Subsequently in 2002, Mathew began a two-year post-doctoral fellowship at the University of Konstanz, Germany, as an Alexander von Humboldt Fellow under the mentorship of professor Richard R. Schmidt, followed by a one-year post-doctoral fellowship at Ohio State University under the mentorship of professor Robert C. Coleman. Following her post-doctoral training, she gained more than 14 years of research experience in medicinal chemistry, heterocyclic chemistry, carbohydrate chemistry, total synthesis of natural products, and discovery and lead optimization of small molecules for the development of novel drugs. Ten of those years have been spent at Southern Research, where she focuses on structure-based drug discovery for cancer and infectious diseases. Mathew has authored several peer-reviewed publications in journals such as Nature Immunology and Journal of Clinical Investigation, and she is an inventor on several patents. She received the Southern Research Excellence Award in 2010 and 2015. Currently, Mathew is working on various collaborative projects between SR and the University of Alabama at Birmingham, such as Heme Oxygenase -1 Activation for Kidney Disease, NF-kB activation for the treatment of ALS, and TSP-1 mediated TGF-β activation for potential treatment of multiple myeloma.