Murray Stackhouse, Ph.D.
As senior scientist in Cancer Therapeutics and Immunology, Murray Stackhouse serves as study director for all in vivo cancer studies at Southern Research. His current research involves the use of xenograft models to screen anti-cancer therapies alone or in combination with other compounds or radiation. His other area of interest involves the use of syngeneic mouse models for the investigation of new immune-oncology therapeutics.
Stackhouse has over 15 years of experience in the design, conduct, and interpretation of in vivo studies with human tumor xenografts, as well as murine tumors. Over the past 14 years, as study director for candidate drug testing for commercial sponsors overseeing more than 50 studies a year, he has gained extensive experience managing in vivo antitumor drug evaluation studies utilizing pathogen-free, immune-competent, and immune-deficient mice. Most recently at Southern Research, he led efforts in drug discovery to establish rodent models for other diseases and injury models (radiation mucositis and SLE).
Before joining Southern Research in 2002 as a study director, Stackhouse was an assistant professor in the Radiation Oncology Department at the University of Alabama at Birmingham. There, he was involved in early gene therapy development for the treatment of cancer, where he focused on the role of gene expression to enhance the radiation sensitivity of human cancer cells. He and his team developed various strategies to enhance the effect of radiation in cancer therapy and had several in vivo studies published utilizing xenograft models.
Stackhouse is a professional member of the American Association of Cancer Research. He has co-authored 29 publications and 30 abstracts. He earned his doctorate in radiation biology from Colorado State University and completed his postdoctoral work at Los Alamos National Laboratory. Stackhouse earned his Bachelor of Arts in microbiology from Weber State University.