Vandana V. Gupta, Ph.D.
Associate Research Chemist
Gupta completed her doctorate in organic chemistry in 2009 from the Central Drug Research Institute, Lucknow, India. Her graduate research experience includes the development of novel antibacterial and antihyperlipidemic analogs. Following graduate school in 2009, Gupta joined GVK Bio, a contract research organization based in Hyderabad, India, as senior research associate, where she gained two years of industrial experience. She then joined Southern Research as a post-doctoral research fellow in 2012, and after three years, was promoted to associate research chemist. At SR, Gupta has been involved in the LRRK2 Drug Discovery program, synthesizing small molecule inhibitors as a potential therapeutic for the treatment of Parkinson’s disease, and more recently, she has been focused on an NIH-funded Cancer program, TSP-1 mediated TGF-β activation for potential treatment of Multiple Myeloma. The main objectives for each of these projects are to design and synthesize novel molecules with superior potency, ADME and PK properties. Each of these programs supports Gupta’s current research interests, which lie at the interface of chemistry and biology, with a focus on the design and synthesis of novel molecules for the treatment of cancer and central nervous system disorders.