Advanced, Reliable, and Rapid ADME and Toxicity Assessments
Southern Research provides expert ADME and In Vitro Toxicology solutions critical for early-stage drug discovery. Our rapid-turnaround, U.S.-based services offer robust scientific insights, flexible protocols, and extensive industry expertise, ensuring accurate and timely results. Whether assessing metabolic stability or predicting cytotoxicity, we streamline your drug development pathway.
What Sets Us Apart:
- Rapid turnaround times for critical ADME and cytotoxicity assays.
- Flexible protocols, accommodating customized testing requirements
- Advanced cytotoxicity (CYTOtox) and mitochondrial toxicity (MITOtox) screening capabilities
- Comprehensive capabilities in evaluating Cytochrome P450 (CYP450) drug metabolism
- Capability to source commercially available custom species for comparative metabolism studies
- Specialized expertise in AMES testing integrated into chemistry workflows
- 20+ years of experience delivering high-quality ADME studies
- U.S.-based laboratories ensuring reliable and timely service
CYTOtox & MITOtox Screening
Rapidly and accurately evaluate compound cytotoxicity and mitochondrial toxicity, leveraging advanced cell-based assays to prioritize compounds for development and reduce late-stage failures.
Mini-ADME and Solubility Testing
Efficiently assess key ADME properties, including solubility, protein binding, and LogD, to quickly determine compound viability and streamline candidate selection.
Integrated Chemistry Workflows
Our integrated chemistry and ADME capabilities provide seamless compound optimization, enabling informed chemical modifications that enhance drug properties and safety profiles.
High-Throughput Screening (HTS)
Leverage our HTS platforms for rapid and precise identification of active compounds, incorporating ADME considerations to optimize your discovery and development process.
Your Trusted Partner in Early-Stage Toxicology & ADME Testing
With decades of proven experience, Southern Research expertly manages critical early-stage ADME and toxicity evaluations. Our validated assays, state-of-the-art facilities, and expert scientific staff provide reliable data, ensuring informed decision-making and regulatory compliance.
Validated Protocols & Regulatory Compliance
Ensure seamless regulatory submissions with our fully validated ADME and analytical assays, eliminating study exceptions and accelerating your IND enabling process.
Customizable Testing & Flexible Study Designs
Our adaptable study protocols accommodate unique client requirements, offering customized testing strategies tailored to meet specific drug development goals.
Our Experts
Donghui Bao, Ph.D.
Joseph Randall, Ph.D.
Erin Luea
Ready to Advance Your Research?
Contact our experts today and explore how Southern Research can elevate your project.