The Chemistry Department within the Southern Research Drug Discovery division houses a team of chemists with extensive experience in both medicinal chemistry and synthetic organic chemistry. Current research and drug discovery programs cover a large range of various disease areas including antivirals and emerging pathogens, Parkinson’s and Alzheimer’s disease, ALS, diabetes, cancer, and psychiatric disorders. One of the Chemistry Department’s main goals is to identify and bring forth compounds that can be classified as potential preclinical candidates and then collaborate with partners to advance these compounds into human clinical trials. Additionally, basic research is carried out as we explore compounds that may be used as tools to investigate novel targets. Several existing collaborative relationships exist between the department and external partners, such as universities, research centers, and the National Institute of Health (NIH). The department encompasses various disciplines in addition to synthetic chemistry, such as structural biology and protein crystallography, computational chemistry and high throughput synthesis and purification capabilities, as well and informatics tools to process and track data.