Category: News

Alabama students explore science at STEM Spring Break Camp

Forget the beach or the mountains. One of the coolest places to be this Spring Break is the lab at Southern Research.

About 80 Central Alabama students are expected to spend this week at the organization’s Southside campus, conducting experiments much like the ones researchers do there every day.

It’s Spring Break Camp, part of expanded STEM education efforts aimed at sparking students’ interest toward careers in the field.

On Monday, students measured the effect of caffeine on cardiovascular function using chick embryos. In some cases, the work didn’t go as planned, as some chicks didn’t have heartbeats.

STEM education Southern Research
About 80 Central Alabama students are attending Southern Research’s STEM Spring Break Camp, conducting experiments much like the ones researchers do there every day.

But that was an important lesson for students, said Kathryn Lanier, Ph. D., Southern Research’s first STEM Education Outreach Director.

“Science doesn’t always work. There’s a lot of trial and error, and they are getting real world career exposure here,” she said.

For Abel Lopez, a senior at Bibb County High School, the camp is meaningful step toward his planned career as a neurosurgeon and medical researcher, a choice he traces to childhood.

“When I was 4, my dad had a brain tumor, and the doctors at UAB saved his life,” he said. “I’m going to be starting UAB in the fall, and I will be the first-generation college student in my family.”

Lopez said the camp has exceeded his expectations, because of the hands-on experiments.

“I’ve toured a couple of other labs, and it was all ‘just looking,’” he said. “This is great. I was not aware we had a place like this so close to home.”

Some of the students participating in this week’s camp are part of Upward Bound, a college preparatory program for students from low-income families and families in which neither parent has a bachelor’s degree. Others are part of the Boys & Girls Club and home school groups.

Southern Research STEM education
Students attending Southern Research’s STEM Spring Break Camp are learning how to conduct experiments and getting a look at a possible career path.

Working with the students are Southern Research scientists, including Michelle Valderas, director of Infectious Disease Preparedness Initiatives, who helped the group with the chick embryo experiment. Her daughter Tori, a sophomore at Vestavia Hills High School, is participating as a volunteer helper all week.

“I hope they learn a little about how to design an experiment and how to look at their results in an objective way,” Valderas said. “I hope they also learn how science isn’t perfect, how our own biases can taint our experimental results and how we can use math to make sure that doesn’t happen.”

Delbra Peoples, a sophomore at Montevallo High School, said she has always been interested in STEM, and events like the camp help her make decisions about her future education and career.

“It’s cool to see the work they’re doing here, and it furthers my knowledge,” she said.

Southern Research STEM education
Southern Research expanded its STEM education program to introduce students to careers in science and engineering.

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Southern Research Advisory Board Adds New Members

The Southern Research Advisory Board added three new members – Alexia Borden, Deon Gordon, and Elizabeth Scribner, Ph.D. – at its 1st Quarter meeting on February 23.

“This is an exciting time for Southern Research, and we are pleased that these three outstanding leaders have chosen to contribute their time and expertise to the Advisory Board as it works to support the organization’s mission of solving the world’s hardest problems,” said board chairman David Perry, Vice President of Corporate Strategy at Protective Life.

Elizabeth Scribner, Ph. D., Deon Gordon, and Alexia Borden (left to right) joined the advisory board at its February 23 meeting.

Alexia Borden serves as the senior vice president and general counsel for Alabama Power. She attended the Georgia Institute of Technology, where she earned a degree in industrial engineering, before attending law school at the University of Alabama. Prior to her 2016 hire at Alabama Power, Borden practiced law in Birmingham and Montgomery for more than a decade, representing clients in environmental and natural resource matters. She also serves on multiple boards across the state, including the Alabama Shakespeare Festival and the Baptist Health Foundation.

Deon Gordon comes to the board from TechBirmingham as the organization’s newly selected president. Gordon formerly served as the director of business growth for REV Birmingham, where he led the launch of the organization’s restaurant incubator REVeal Kitchen, located in the Pizitz Food Hall. He serves on a variety of city boards, including the Railroad Park Foundation, Birmingham Artwalk, Growing Kings, and the Commercial Development Authority of the City of Birmingham, and was the 2017 recipient of the A.G. Gaston Award for Outstanding Community Service. The same year, Gordon was also recognized by the Birmingham NAACP in its annual Salute to Outstanding African-Americans. Last month, he was named to the Birmingham Business Journal’s annual Top 40 Under 40.

Elizabeth Scribner, Ph.D., joins the advisory board as a representative of Regions, where she works as an analyst in model risk management and validation. She received her undergraduate degree in History and Environmental Studies from Princeton University, and holds both a masters and doctorate in mathematics from UAB. In addition to her role at Regions, Scribner works as a technical advisor for Eagle Solar & Light, Birmingham’s first full-service solar installation and LED lighting company, and assists in the company’s educational outreach. Previously, she taught mathematics at Mountain Brook Junior High. Scribner also holds a position as a board member for the Kaul Foundation and the Greene Scholarship Committee.

“The addition of these new members will further bolster Southern Research’s relationship with the Birmingham business community,” said Watson Donald, SR Senior Director of External Affairs. “They, along with our existing advisory board members, will provide us with valuable feedback in many of our scientific and engineering endeavors as they continue to advance in their own respective careers.”

In addition to Perry, existing board members include Stephen Black, Director, Center for Ethics & Social Responsibility at the University of Alabama; Jay Brandrup, Principal at Kinetic Communications; Nick Irvin, Director of Research and Development for Strategy, Advanced Nuclear, and Croscutting Technology at Southern Company; G.T. LaBorde, CEO at IllumiCare; Danny Markstein, Managing Director at Markstein; Liz Pharo, Chair at Momentum Telecom and Managing Partner at Featheringill Capital; Shannon Riley, President and CEO at One Stop Environmental; and Mitesh Shah, Shareholder at Maynard, Cooper & Gale, PC.

The Southern Research Advisory Board was established in 2015 to engage emerging business leaders in the Birmingham community who are committed to enhancing Southern Research’s mission of scientific and engineering advancement.


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Expanded ‘real-world STEM’ program targets student excitement

Southern Research’s expanded STEM education efforts are making a difference in classrooms across Alabama, and even more students are in line to benefit from the program in the coming weeks and months.

A highlight was the Black History Month Science Fair, which Southern Research sponsored recently with Alabama Public Television and Birmingham Children’s Theatre.

Students were asked to create a project that complemented the research of a famous African-American scientist or engineer. The event, which drew 500 people, was held at Birmingham Children’s Theatre.

Southern Research STEM
Kathryn Lanier, who leads Southern Research’s STEM education program, engages with students.

It was followed by a performance of Rosa Parks and The Montgomery Bus Boycott and a panel discussion with African-American scientists and engineers who work at Southern Research and NASA.

The educational aspect was significant, but just the trip to Birmingham was meaningful for many students, said Anna Wheeler, a sixth-grade science teacher from Escambia County Middle School in Atmore.

“A lot of my students had never even been out of Atmore, so just the simple fact that they were invited to go to an event in another city and present their ideas was mind-blowing to them,” she said. “A lot of them were hesitant to even send in something because they didn’t think their ideas were good enough, so it was definitely a boost of confidence to be accepted into the science fair.”

As their buses traveled into downtown Birmingham, students were excited to see big buildings, and they were amazed by the expressway that runs through Red Mountain.

“The amount of pictures taken on the bus was unbelievable. We had a mini science lesson on how they carved through that rock,” she said.

Wheeler said the event was a huge stepping stone for all of the students.

“It really got them motivated,” she said. “A lot of students I don’t usually see participate in STEM activities came out of their comfort zone to create projects and make presentations. They can’t wait to do it again next year.”

ENGAGING STUDENTS

Kathryn Lanier
Students pose with their awards at Birmingham’s inaugural Black History Month Science Fair, a partnership between Southern Research, Alabama Public Television and the Birmingham Children’s Theatre.

That excitement is a key goal of Kathryn Lanier, Ph.D., Southern Research’s first STEM Education Outreach Director. Since joining the non-profit organization last year, she has been busy planning events and designing experiments.

“Working on solutions to real-world problems is the heart of any STEM investigation. And that is what our program is doing,” she said. “We are deeply committed to engaging the students in true project-based learning.”

Lanier is serious about the impact of her work, as well as the importance of showing students what a STEM career looks like.

“Our No. 1 priority is to expose students and teachers to real-world STEM,” she said. “We want to give them an experience they can’t get inside the walls of their classroom. So, when I’m designing experiments, I want to make sure it reflects the work we’re doing at Southern Research.”

For example, at an upcoming Spring Break Camp at Southern Research, students will measure the effect of caffeine on cardiovascular function using chick embryos.

“While our drug development researchers aren’t necessarily testing caffeine, they are using chick embryos to test other drugs, and we’ll utilize many of the same techniques,” Lanier said.

This summer, a new STEM lab is scheduled to be complete, giving Lanier much-needed space to regularly host larger groups of students. It will be outfitted with 3D printers, robotics equipment, coding software, drones and other features to support an interdisciplinary approach.

Southern Research STEM
Kathryn Lanier, Southern Research’s STEM outreach director, shows students an experiment.

“By using a space that integrates engineering and technology into science, we’re combatting the misconception that science can be learned through a single lens,” Lanier said.

“Most importantly, teachers can bring their entire classes, because the lab will be able to accommodate 50 students at a time. While our scientists and engineers love hosting students in their labs, they do have important jobs solving the world’s hardest problems.”

SHARING A NEW WORLD

Lanier, who holds a doctorate degree in biochemistry from the Georgia Institute of Technology, said her own journey with STEM education was challenging at times, and that’s something she shares with students today.

But she stuck with it, because she fell in love with research and the pursuit of solving problems. She was also encouraged by teachers and mentors, who showed her a new world of possibilities.

“Kids start developing ideas of what they’re good at when they’re very young, and if they’ve never been exposed to science and engineering they’re never going to realize their potential” she said.


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Prosperity Fund supports growth of Alabama bamboo industry

Could Alabama become home to a major new industry centered on bamboo farming and product manufacturing?

Southern Research and its Prosperity Fund initiative are teaming up with Resource Fiber, a bamboo fiber products company, to help realize the commercial potential of bamboo in a state known for thick pine forests.

Marsha Folsom, Resource Fiber’s Chief Development Officer/Governmental Affairs/Economic Development, said The Prosperity Fund has connected the firm with Alabama businesses interested in exploring industrial applications of bamboo and university professors who want to do bamboo research.

Meanwhile, Southern Research’s testing facilities are evaluating company bamboo products to determine strength and other important characteristics to advance their product development efforts.

“We are very excited about the prospects for the future with Southern Research and its Prosperity Fund and what this collaboration will do for the expansion of economic development around the mass cultivation of bamboo and manufacturing of bamboo industrial products in Alabama, a first for the U.S.,” Folsom said.

Resource Fiber Southern Research
Southern Research and its Prosperity Fund initiative are providing testing services to Resource Fiber, a firm that wants to launch mass cultivation of bamboo and manufacture bamboo industrial products in Alabama.

She added that one of Resource Fiber’s goals is to act as a magnet to attract other industries interested in utilizing bamboo fiber to Alabama and the region.

“Collaboration with Southern Research serves as a key component to making that happen,” Folsom said.

EXPANDING RELATIONSHIP

Steven Puckett, managing director of The Prosperity Fund, said the economics of bamboo are compelling. Bamboo grows rapidly, up to two feet per day, and it yields 20 times more fiber than trees, with no replanting necessary. Plus, it requires little water and no pesticides.

Estimates show that bamboo could yield considerably more revenue per acre annually than pine, Puckett said.

“Bamboo cultivation and product manufacturing could one day become a significant new industry in Alabama, and that’s why The Prosperity Fund is keenly interested in its future possibilities,” Puckett said. “We are committed to investigating innovative solutions that spark job creation and foster sustainable growth through a new brand of economic development.”

The testing of bamboo samples is now underway at Southern Research’s Birmingham engineering facilities, focusing on factors such as strength and flammability that are integral to product development.

“Southern Research is performing testing on the bamboo product as the company moves forward to achieve the certification needed for commercial use,” Puckett said. “Certification is an expensive process, and we are helping work out all the kinks as they prepare for the certification process.”

Southern Research Resource Fiber
Southern Research and its Prosperity Fund initiative are providing testing services to Resource Fiber, a firm that wants to make bamboo industrial products in Alabama.

Folsom said the testing at Southern Research will provide Resource Fiber with performance information before it sends product samples to third-party laboratories for industry certification. Securing that certification is key to market acceptance for the company’s products, which include bamboo rail ties and bamboo nail laminated timbers for the construction industry.

She expects Resource Fiber to work with the Prosperity Fund to expand the testing to other products in the future.

“We see this collaboration continuing and hopefully expanding into the future. A myriad of products can be made from bamboo,” Folsom said. “Through collaboration and drawing on the respective expertise from both Resource Fiber and Southern Research, we can establish Alabama as the epicenter of bamboo research, bamboo farming at scale, and bamboo manufacturing expertise in the U.S.”

GROWTH POTENTIAL

While bamboo represents a $60 billion industry worldwide, there hasn’t been much of an attempt to capitalize on it in the United States, according to Resource Fiber, which calls itself the nation’s only vertically integrated bamboo fiber products company.

Resource Fiber now operates a 100-acre in-field bamboo nursery in Greene County, located in Alabama’s “Black Belt,” named for the rich, fertile soil that made it a key cotton-producing region. With the doubling of the size of its nursery, the company expects to provide enough plants to populate 100,000 to 150,000 acres of bamboo over the next decade.

Southern Research Prosperity Fund
A Southern Research technician splits a piece of bamboo as part of testing conducted for Resource Fiber, which wants to launch a bamboo industry in Alabama.

While much of Resource Fiber’s focus is on the Black Belt, its growth potential has implications for the Alabama coal counties targeted by The Prosperity Fund. The company intends to move its production facility to Tuscaloosa County, and Puckett has connected it to support businesses in Walker and Jefferson counties already.

“As the bamboo economy grows in Alabama, we fully expect many more counties other than those in the Black Belt to benefit through expanded manufacturing of bamboo products utilizing bamboo fiber grown in Alabama,” Folsom said.

With financial backing from the Appalachian Regional Commission, Southern Research formed The Prosperity Fund in 2017 to accelerate small business growth and job creation in four Alabama counties hurt by the coal industry’s downward spiral.


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Prosperity Fund teams with UA students to assist Walker County timber industry

Southern Research’s Prosperity Fund is collaborating with students from the University of Alabama’s STEM Path to the MBA program to explore strategies to improve the fortunes of Walker County’s forest products industry.

The UA students, working with Prosperity Fund Managing Director Steven Puckett on a yearlong research project, are investigating a wide range of ways to spur a comeback for the industry in a county already battered by the coal downturn.

The students are evaluating possible new uses for Walker County’s vast timber resources, including engineered wood panel systems used in construction projects. They’re also studying unconventional solutions such as the viability of bamboo farms to augment the county’s sprawling pine tracts.

“We’re working as a team to develop concrete recommendations that will help this important industry in Walker County move toward more fully reaching its potential,” Puckett said. “We’re searching for ideas that could lead to job creation and provide a boost to small businesses in the county.”

Southern Research Prosperity Fund
Students in the University of Alabama’s STEM Path to the MBA program are helping the Prosperity Fund understand the problems facing Walker County’s timber industry.

With financial backing from the Appalachian Regional Commission, Southern Research formed The Prosperity Fund in 2017 to accelerate small business growth and job creation in four Alabama counties hurt by the coal industry’s downward spiral. Besides Walker, the counties are Fayette, Tuscaloosa and Jefferson.

‘ECONOMIC ROLLER-COASTER’

Troubles for Walker County’s forest products industry began shortly after the loss of 500 coal jobs. In 2014, a paper mill in Courtland – about 70 miles from Jasper and the chief consumer for Walker County wood fiber – shut down after 40 years of operation.

The mill’s loss has dealt a heavy blow to the industry across the region, said Paul Kennedy, president of the Walker Area Community Foundation, a partner in The Prosperity Fund.

“The forest products industry is a traditional economic roller-coaster,” Kennedy said. “This time, the roller coaster got to the bottom of the hill, and there was nothing to pull it back up.”

Today, Puckett said harvesters in Walker County must transport their product – essentially a bulk commodity with a low per-unit value — great distances under extremely uneconomical conditions.

“In Walker County, the producers have all this land and all these trees, but nowhere nearby to take it,” he said. “They have to take their loads about 150 miles one way, which means they travel all that way to make a delivery, then deadhead it back with nothing.”

REAL-LIFE LEARNING

The UA students got involved when Puckett approached Pamela Hill, a clinical instructor in the STEM Path to the MBA program, which allows high-achieving undergraduate students majoring in STEM disciplines to earn an MBA in an additional year.

Student Alex Jaffery said the UA team has been engaged in finding new solutions to improve the use of Walker County’s natural resources. His role has been to research alternative products, specifically bamboo. He served as a liaison with a company called Resource Fiber that’s seeking to commercialize bamboo.

“I learned a lot about business optimization in the project. In the program we also learned about formulating business models,” Jaffery said. “With the project I was able to formulate and apply a business model to a real-life situation.”

Other UA students working with the Prosperity Fund are Tyler Matthews, Tom Kobitter and Nichole Cheatum.

EXPLORING NEW OPTIONS

University of Alabama
Collaborating with the Prosperity Fund are University of Alabama students Alex Jaffery, Tyler Matthews, Tom Kobitter and Nichole Cheatum.

Puckett said the UA students have focused on identifying catalysts that could spark growth in Walker County. One idea centers on cross-laminated timber, or CLT, an engineered wood panel system that is increasingly used in construction projects, particularly in Europe.

The students have been willing to think outside the box. Their research determined that pine trees yield about $54 an acre over 20 years. Bamboo, on the other hand, can yield between $700 and $1,500 per acre. And once it’s established after seven years, bamboo can be harvested every year.

“There’s a huge difference in value,” Puckett said. “If bamboo could be introduced on a meaningful scale and markets found for it, that could produce a substantial potential economic impact on the county.”

The student group has also met with several large companies involved in land management in Walker County. One company is intrigued by their bamboo idea; this spring, a test plot will be planted on reclaimed mine land as an experiment, Puckett said.

In addition, a lumber company in Jasper is evaluating a cost-saving suggestion advanced by the students. The company currently imports expensive exotic wood from South America to use as spacers in its wood kilns. Tests will show whether bamboo grown and processed in Walker County serve the same purpose more cheaply.

One unconventional idea being explored involves planting lavender on a commercial scale on reclaimed mine lands for sale to industrial producers of essential oils.

Kennedy at the Walker Area Community Foundation is grateful for the students’ involvement and isn’t concerned that some ideas likely won’t fly. He recalled an anecdote about inventor Thomas Edison saying 300 failures taught him valuable lessons.

“If the students can take us through the 300 ways that won’t work for our forest products industry and get us to the one way that actually lights up and changes the world, that’s what I’m after,” Kennedy said.

Corey Tyree, director of strategic growth initiatives at Southern Research and a co-founder of the Prosperity Fund, said he is confident the students will develop actionable recommendations that could benefit the forest products industry in Walker County.

“The Prosperity Fund operates by harnessing available resources and identifying innovative solutions to difficult problems holding back industries and communities,” Tyree said. “Our work with these talented University of Alabama students to assist Walker County’s timber industry aligns perfectly with that strategy.”


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Low-cost carbon fiber project advances to pilot phase

The U.S. Department of Energy (DOE) has selected Southern Research for an award of up to $5.9 million to advance production of high-performance, low-cost carbon fibers from biomass. The DOE award will fund development of a multi-step catalytic process for conversion of sugars from non-food biomass to acrylonitrile – a key precursor in the production of carbon fiber.

Thanks to its high strength and light weight, industrial demand for carbon fiber continues to grow in a number of fields, including defense, space, aviation, automotive, wind turbine production, and sporting goods manufacturing.

At its Durham, North Carolina facility, Southern Research is developing a method of producing acrylonitrile and other bio-based chemicals using renewable, non-food-based biomass feedstocks.

The DOE’s initial award, announced in July 2014, was divided in two stages. Phase I called for the completion of lab-scale studies to demonstrate the process and verify techno-economic viability. Phase II consists of constructing and operating a pilot plant to scale up the process to produce kilogram levels of acrylonitrile, while demonstrating process reliability and product validation.

Southern Research carbon fiber
The Southern Research team working on a process to make low-cost carbon fibers from biomass has secured funding to move the project to pilot production phase.

Southern Research successfully completed Phase I work in 2017 and met all DOE milestones. In late November, DOE authorized Phase II of the project, and Southern Research has started pilot plant construction.

Bill Grieco, Ph.D., vice president of Southern Research’s Energy & Environment, said the organization’s process for producing acrylonitrile from biomass promises to change the economic and environmental footprint for the carbon-fiber supply chain.

“The use for carbon fiber is increasing as manufacturers look to increase strength while also reducing weight of their products. Those manufacturers are also demanding lower cost and sustainably produced carbon fiber,” Grieco said.

“By focusing on the conversion of biomass-derived sugars to acrylonitrile, the key raw material in the highest-quality carbon fiber, Southern Research is enabling low-cost carbon fibers without any compromise in product performance.”

CHEAPER, CLEANER PROCESS

The process developed by a Southern Research team lead by Amit Goyal, Ph.D., associate director and the principal investigator on the project, produces acrylonitrile that is around 20 percent cheaper than conventional production methods. The process also results in a 37 percent reduction in greenhouse gases.

“At Southern Research we have developed an innovative, elegant process that utilizes biomass derived sugars from any source, allowing for the use of a variety of biomass feedstocks, to produce acrylonitrile,” Goyal said.

Southern Research carbon fiber
This graphic shows Southern Research’s process that converts biomass to acrylonitrile, a precursor of carbon fiber.

“This process could not only potentially improve economics, but may also improve the overall environmental footprint of carbon fiber production when compared to traditional manufacturing methods.”

Team members on the project include Solvay Composite Materials (formerly Cytec Carbon Fiber, LLC) and New Jersey Institute of Technology (NJIT). The bio-based acrylonitrile produced by Southern Research’s process will be validated by Solvay, a major carbon fiber manufacturer, and compared with petroleum-based acrylonitrile as a potential direct substitute. NJIT will assist with catalyst characterization for optimizing catalyst performance.

“Solvay is very excited about the importance of this research and our ability to be a trusted and valued partner in the development of the next dimension of carbon fiber technology,” said Billy Harmon, carbon fiber research and innovation director for Solvay.


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Southern Research programs aim to shield against pandemic flu dangers

With experts predicting another deadly influenza pandemic in the future, Southern Research scientists are working on several fronts to help limit the death toll from a catastrophic flu outbreak that one day slams the nation.

Birmingham-based Southern Research conducts tests on emerging pandemic strains and participates in strategic government vaccine programs focusing on highly pathogenic avian influenza (HPAI) strains that pose potentially grave public health risks.

In addition, Southern Research has performed toxicology studies for flu vaccine platforms and provided pre-clinical studies on vaccine candidates, along with clinical trial support for vaccine makers. The non-profit organization has also researched antiviral treatment approaches that could protect people after infection.

“Scientists will tell you it’s not if, it’s when we have a pandemic. That’s the way the flu virus works,” said Landon Westfall, Ph.D., a senior project manager and infectious disease scientist at Southern Research. “It’s like the San Andreas fault – the big one is coming one day. The idea is since we can’t prevent it, we should prepare for it. That’s the goal.”

pandemic influenza Southern Research
The last global flu pandemic, the 2009 H1N1 swine flu outbreak, killed as many as 575,000 people across the globe.

Pandemic influenza strains pose much a greater threat than even the nastiest strains of seasonal flu. The dominant seasonal strain this year, H3N2*, fits that description, causing an above-average rate of hospitalizations and prompting Alabama to declare a public health emergency.

The current flu season’s misery is worsened by the fact that the available vaccine is only moderately effective.

“That’s the challenge with flu. Vaccines don’t always work,” Westfall said. “Most of the time, they protect 55 to 60 percent of the population. That’s kind of the goal of influenza vaccines. But there will always be subsets of the population that won’t be protected.”

ELEVATED DANGERS

Novel avian or swine flu strains, however, have the potential to cause lethal damage on a global scale. Because these dreaded strains are new, very few people have immunity against them, so they can spread widely and rapidly, sickening a large segment of the population, Westfall said.

When pandemics emerge, more than half of an affected population can be infected in a single year, while the number of deaths stemming from the flu outbreak can sharply exceed normal levels.

That’s why the work being conducted by Southern Research and other organizations as part of the U.S. government’s influenza preparedness programs is critically important, Westfall said.

The goal is to prevent a global calamity like the 1918 Spanish flu pandemic, which killed more than 50 million people, and outbreaks in 1957 and 1968 that each killed at least 1 million people worldwide. The last pandemic, the 2009 H1N1 swine flu outbreak, killed as many as 575,000 people. More information on pandemics.

pandemic flu Southern Research
Landon Westfall is a senior project manager and infectious disease scientist at Southern Research.

For more than a decade, pandemic fears have centered on the highly lethal H5N1 avian influenza, despite the fact that the so-called “bird flu” virus does not infect humans easily. If a mutated form of the H5N1 virus became easily transmissible from person to person while retaining its severe effects, the public health consequences could be very serious, the World Health Organization warns.

“For the most part, avian influenza affects birds. When the virus makes a jump for one species to another, say from bird to human, that’s a big thing,” said Westfall, who oversees the influenza virology program for Southern Research’s Drug Development division. “That’s a rapid evolution for a virus that will likely cause major problems. In cases, where the avian flu has infected humans, the mortality rate has been around 60 percent.”

Southern Research scientists have worked on influenza projects for government agencies including the National Institutes of Health, the National Institute of Allergies and Infectious Diseases, and the Biomedical Advanced Research and Development Authority. The organization has also worked with a number of commercial clients.

“We’re recognized as one of the leading supporters for clinical vaccine research, especially for flu,” Westfall said. “That is partly because of our history in the field but also because of our capabilities to test a large volume of samples in a relatively short time.”

THE NEXT PANDEMIC

Southern Research flu pandemic
The H1N1 virus triggered a global influenza pandemic in 2009.

Although most experts believe another influenza pandemic is inevitable, Westfall said it is impossible to predict when or where it will occur, or how severe its impact will be. It’s almost impossible to predict with certainty the subtype of influenza virus most likely to cause the next worldwide outbreak.

Late in 2017, scientists reported that a new strain of H7N9 avian flu circulating in China showed the ability to transmit easily among animals with highly lethal results, raising alarm about its potential to trigger a global human pandemic.

While the Centers for Disease Control and Prevention says the risk of H7N9 is currently low because human-to-human transmission is rare, the CDC still rates the strain as having the greatest potential to cause a pandemic.

Westfall said the evolving nature of influenza viruses presents tough challenges to the research community.

“Flu is like a malleable pathogen that can change from week to week, from month to month, and from region to region,” he said. “Every person who gets infected with the flu basically creates a small change in that virus that’s then passed on to multiple people. Flu constantly changes that way.”

*In the designation of influenza subtypes, the H refers to hemagglutinin, a protein found on the surface of flu viruses, while the N refers to viral neuraminidase, another protein present on the surface of the virus.


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Southern Research honors 2017 Excellence Awards Winners

Southern Research honored winners of its 2017 Employee Excellence Awards in a program last week.

The 23 winners include both technical and administrative staff and represent Southern Research across its diverse divisions and departments. All have shown a deep commitment to Southern Research’s mission, its sponsors, and their colleagues.

Their accomplishments supported Southern Research in a wide range of efforts during 2017, from advancing science and technology to making the organization a safer, more efficient, and more productive workplace.

This year, President and CEO Art Tipton, Ph.D., recognized Chuck Hebert, Ph.D., for his contributions and dedication to Southern Research with The President’s Award.

Southern Research
President and CEO Art Tipton recognizes Chuck Hebert for his contributions and dedication to Southern Research with The President’s Award. Hebert is a principal investigator on multiple significant toxicology contracts.

Hebert, a principal investigator on multiple significant toxicology contracts, was acknowledged for leading teams to achieve excellence in study quality, delivery, and budget adherence for high-profile programs including the National Toxicology Program, the National Institute of Mental Health, as well as multiple National Cancer Institute programs.

“Over a 23-year career at Southern Research, Hebert has brought great insight into the organization’s major efforts in toxicity, specifically for reproductive toxicology,” Tipton said. “These efforts ensure the safety of consumers through rigorous scientific programs. Chuck has also been an exemplary mentor for many on our scientific staff.”

As part of his award, Hebert was presented with the Thomas Wesley Martin Medal. A limited number of these coins were made in 1961 as a gift to the board of trustees to show appreciation for a select number of scientists who have made phenomenal achievements in their respective fields.

Receiving Excellence Awards for their work in 2017 were:

Eclipse On-Site Mission Team: The recent mission to collect rare and unique imagery of the 2017 Solar Eclipse with Southern Research’s high-definition imaging system deployed on NASA WB-57 aircraft was a challenging and successful mission that would not have come to fruition without the help of Southern Research team members Don Darrow, Tony Casey, John Wiseman, Ph.D., and Kenny Deerman.

Carol Lackman-Smith: In her 25-plus years of excellence and dedication to SR, Lackman-Smith has strengthened the virology program at the Drug Development facilities in Frederick, Maryland, to meet the highest standards.

Anna Manuvakhova: Playing a multifaceted role on the High Throughput Screening Informatics team, Manuvakhova recently identified an improvement used to normalize data in single dose versus dose response assays. Her meticulous, persistent attention to these details was critical for SR.

Ben Carmichael: Carmichael has worked diligently as a ground test coordinator to ensure the performance of Engineering’s Hypersonics Structures Group is elevated to higher standards. He has, on more than one occasion, displayed exemplary commitment to his job to ensure on-time and accurate delivery to customers when workload was high, and while time until the submission deadline was limited.

Omar Moukha-Chafiq, Ph.D.: Moukha-Chafiq has made a significant impact in many ways to the Chemistry Department and our drug discovery efforts, including identifying key compounds to be used in animal studies to advance programs in Parkinson’s and diabetes.

Lindsey Chatterton: Due to her impeccable lab work and data interpretation, Chatterton has played a major role in working on two large Department of Energy-funded projects. She was recognized for her focused attention to detail in the lab and on proposals.

John Cook: As supervisor of non-destructive characterization lab, Cook has played a critical role in support of a key project for one of Engineering’ s primary customers. While handling these very tight timelines, he continued to support and supervise other key laboratory activities.

Jacques Cuneo: On top of his normal workload, Cuneo proposed and won a major aerospace firm for material characterization in support of a critical defense mission. Cuneo has put countless hours into developing the customers and preparing winning proposals that demonstrated technical excellence and emphasized Southern Research’s unique engineering capabilities.

LaJuana Durbin: Implementing site-wide improvements, Durbin has allowed SR to streamline its processes in the Drug Development division.

Southern Research
Southern Research honored winners of its 2017 Employee Excellence Awards in a program. The 23 winners represent Southern Research across its diverse divisions and departments.

Adela Flores: As a technician in the Cell Biology and Immunology Group within Drug Development, Flores has consistently demonstrated a level of technical and professional excellence. She is relied on to not only execute the most challenging of laboratory techniques, but to also train others in the performance of those assays.

Eriel Martinez-Gutierrez, Ph.D.: Martinez-Gutierrez, a postdoctoral researcher in the Biological Sciences Department, has made outstanding contributions to the field of the important bacterial pathogen Pseudomonas aeruginosa.

Johnny McCullough: Responsible for export control at Southern Research, McCullough has significantly enhanced the management of SR’s import and export activities through his proactive approach to procedures and processes. He has ensured that SR is doing a high-quality job of handling foreign goods vital for our clients.

Kenneth Nicholson: A multi-tasker in the Engineering Materials Department, Nicholson has worked on a multitude of projects with short timelines and high volumes of machined specimens. It is estimated that Nicholson has been the primary machinist on over 700 specimens and every single specimen has met specifications.

Steven Orr: In his new role as the responsible official and manager of biosafety compliance, Orr has helped ensure that the transition in biosafety leadership was handled with a strong emphasis on training and teamwork. He was recognized for his hard work, dedication, flexibility, and his safety-driven focus and leadership in this role.

Tim Robertson: SR has evaluated various types of main tank insulation for NASA’s Shuttle Orbiter and Space Launch System (SLS) programs. The challenge of these projects is that any inefficiencies associated with testing can result in an additional 10 percent in material costs. Robertson has being running specimens for NASA and other aerospace firms for the past 10 years without any issues associated with delays or additional charges.

William Crews: Responsible for managing the sustainable chemistry program at the Energy & Environment facility in Durham, North Carolina, Crews has been a key mentor and project manager allowing for a critical Apollo project to move forward without delay.

Brynne MacCann: Working tirelessly to build a philanthropic program at Southern Research from the ground up, MacCann portrays excellence in her community outreach efforts to donors as well as fostering a culture of philanthropy within the organization. She has demonstrated a strong passion for contributing to the growth and overall success of Southern Research.

Nina Ogden: As External Affairs coordinator, Ogden went beyond her duties to assist the Energy & Environment team with the first Southeastern Energy Storage Symposium.

Rossi Carlson: Responsible for raising visibility and awareness of Southern Research in the community, Carlson has managed multiple events this year that have increased public awareness and engagement in the organization.

The Prosperity Fund brings new growth approaches to Alabama’s coal region

Southern Research’s Prosperity Fund is working to create jobs and boost economic activity in Alabama’s coal region by developing big ideas while always thinking small — small business, that is.

The Prosperity Fund’s efforts in Walker, Fayette, Tuscaloosa and Jefferson Counties concentrates on providing support to bedrock small enterprises and aspiring business owners in communities whose fortunes have long been tied to the coalfields.

As the recognized heart of the nation’s jobs engine, small business should play a larger role in economic development efforts today, according to Corey Tyree, Ph.D., a co-founder of The Prosperity Fund and a director in Southern Research’s Energy & Environment division.

“For a long time, economic development has been about attracting large businesses to your region, and there was a good reason for that,” Tyree said. “But small businesses create two-thirds of U.S. jobs, and there are more things we can do to help them.

“We want to help retain and grow existing small business and help create new ones,” he added.

Southern Research coal
The Prosperity Fund is a $2.4 million initiative led by Southern Research that seeks to create jobs and inject economic vitality into four Alabama counties hit hard by the downturn of the coal industry.

The Prosperity Fund, created with significant backing from the Appalachian Regional Commission (ARC), begins its work at a time when many Alabama coal-mining communities are showing signs of prolonged distress.

Jobs lost in the coalfields aren’t being replaced quickly enough, and new businesses aren’t springing up to fully replenish the economic activity that’s slipped away. The fact that the coal slump followed on the heels of “The Great Recession” just made matters worse.

Alabama’s coal job losses have been heaviest in the four-county area, where some families have worked in mining for generations. The 2,505 coal jobs lost there between 2011 and 2016 represent 10 percent of all U.S. job losses in the sector.

CHALLENGING CONDITIONS

Despite some stabilization this year, many in Alabama’s coal communities doubt the industry will ever regain its traditional role as an economic pillar and job creator in the area.

“I don’t see the industry coming back to its heyday for two reasons – one is mechanization, which has reduced the need for the headcount that mines used to have, and the second is that natural gas prices are just overly competitive compared to coal,” said Paul Kennedy, president of the Walker Area Community Foundation in Jasper.

Fayette County Probate Judge William Oswalt said economics are working against a comeback for coal mining.

“It’s going to be hard to convince a group of investors to come in and spend $700 million or $800 million to develop a coal mine,” Oswalt said. “I’m not hopeful.”

Coal mining has long played an important role in the region served by the Prosperity Fund. In 1997, Jefferson County alone produced 10.4 million tons of coal, making it one of the Top 15 coal-producing counties in the U.S., according to ARC data.

Coal jobs were plentiful that year. Jefferson County had 2,052 coal miners, while Tuscaloosa County had 1,750, the ARC data says. Coal mining jobs numbered 750 in Walker County, and 375 in Fayette County.

The region looks a lot different today.

As this year began, Jefferson County had 1,198 coal miners, a 42 percent decrease in one generation. Tuscaloosa County’s coal miners totaled 397, a decrease of 77 percent. Walker County’s total dropped slightly to 644, according to ARC data.

Fayette County, meanwhile, has lost all its coal mining jobs.

A MINE CLOSES

The harsh blow fell on Fayette County in 2013, when Walter Energy shut down its North River Mine near Berry, saying its coal reserves were running low after 40 years of operation. Some of the 320 or so miners were able to transfer to other Walter mines in Tuscaloosa, but many of them simply saw their paychecks come to an end.

“We had people who were making $60,000 or $70,000 a year digging coal, with benefits, with retirement, lose their jobs,” Oswalt said.

The pain is still being felt. Today, some of these miners remain out of work after decades in the mines because employers see them as too old to start a new career and unwilling to accept wages that fall short of the pay of the lost mining jobs, he added.

The closing of North River Mine also delivered a devastating blow to the finances of Fayette County, wiping out coal severance tax revenue that brought in $500,000 for the county’s general fund annually, Oswalt said.

“It’s been brutal. We have absolutely no means of replacing that. Zero. We had been drawing that revenue for the last 30 years,” he said. “You wake up one morning, and it goes to nothing.”

When Walter closed the North River Mine, the company planned to invest $1.2 billion in a massive new mining operation that would open by 2019 with 450 jobs in northeast Tuscaloosa County.

That project died, and Walter slid into bankruptcy.

BLUEPRINT FOR RECOVERY

Corey Tyree is director of strategic growth initiatives for Southern Research and a co-founder of The Prosperity Fund.

The kind of concentrated job losses affecting Fayette County have magnified the coal downturn’s negative effects in many Alabama communities, adding to challenges that were already present.

For one thing, wages have been lagging in much of the four-county area. Fayette County’s per capita income in 2014 was $19,356, only slightly more than half of the U.S. average. Walker County’s figure of $25,993 was 78 percent of the national average, according to data from the Economic Innovation Group, a bipartisan public policy organization.

Another challenge is that entrepreneurial activity is low through much of Alabama’s coal region, which creates a negative cycle in a struggling community. With few new businesses being formed in these communities, economic fragility increases and some residents depart for areas offering more opportunity.

So the big question is: How can Alabama’s coal country bounce back from a devastating downturn that appears lasting?

Tyree believe the answer lies with new approaches to help small businesses in the region become healthier.

The Prosperity Fund’s focus in on helping nurture small businesses so they can grow and hire new workers, as well as lending support to get promising new ventures off the ground. It has hired a veteran entrepreneur, Steven Puckett, to work with businesses in the region.

The initiative will collaborate with existing businesses, colleges and universities, economic development groups, potential investors, and community leaders throughout the region. It’s working with businesses to find new customers, improve efficiency and update their technology and processes.

The Prosperity Fund is also developing broader small business programs such as workshops focused on small business procurement, lending, human resources, and more.

FINDING RESILIENCE

Leslie C. Hartley, Ph.D., dean of instruction and interim executive vice president at Bevill State Community College, agrees that a new way of looking at economic development is needed in the area.

“The economic development of today is focused on human capital building. That’s where we’re going today – building the human capital we already have in our area,” she said. “There are so many niches of talents and ideas, and there are lots of opportunities for individuals in our community to be more prosperous.”

Tyree believes that Southern Research, which was founded in 1941 to drive economic development in Alabama, is the right organization to help small enterprises and struggling communities in Alabama’s coal belt.

“Regions with strong entrepreneurial cultures bounce back faster from economic downturns. Unfortunately, that sort of economic resiliency is increasingly something seen only in a few urban areas. We’ve got to work to change that,” Tyree said. “We want to work with community leaders who can introduce us to the folks who need our help.”

Oswalt said he believes small business growth and increased entrepreneurial activity would provide a boost for Fayette County.

“If I could get a new company that employs 10 people, I’d shout,” he said. “That would be a huge victory.”

Southern Research coal

Southern Research hosts 70 Alabama students for STEM Day

High school students from across Alabama got a hands-on learning experience at Southern Research on Tuesday.

More than 70 students, who hail from Jefferson, Walker, Blount, Talladega and Morgan counties, were part of the organization’s STEM Day activities.

The event showcases Southern Research’s far-reaching capabilities involving drug discovery, drug development, engineering, energy and the environment, while offering a glimpse into the daily routine of scientists and researchers.

“I’m excited to get my hands on some really cool technology,” said Tavaria Johnson, a sophomore at Childersburg High School.

Southern Research STEM outreach
More than 70 students from across Alabama participated in Southern Research’s STEM Day activities.

Johnson said she plans a career in neurosurgery, and she’s fascinated by the advancements in drug development that have shed new light on the body’s nervous system.

“We have these diseases that people don’t think are curable, but we also have these awesome scientists who work daily to solve these problems,” she said.

STIMULATING INTEREST

STEM Day is designed to get students excited about science, said Kathryn Lanier, Ph.D., the organization’s first STEM Education Outreach Director.

“We want them to see what the life of an everyday scientist looks like,” she said. “A lot of these students don’t have exposure to what an actual career in science and engineering would look like. This is a great time for them to come and experience firsthand what our scientists and engineers do.”

Half of the students spent the day at Southern Research’s Southside campus, while the other half visited the Oxmoor campus. At both sites, they ate lunch while scientists and engineers gave an overview of their work.

The students included those from Childersburg, Ramsay, Holy Family Cristo Rey, Homewood, Jasper and Falkville high schools. Local homeschool students also were a part of the group.

Beth Kennedy, vice principal and director of career and tech education at Jasper High School, said STEM Day offers students valuable insight.

“Every time we can get them into a working environment and every time we can expose them to scientists and professionals in a field they’re interested in, they can see that this can be their future,” she said. “This is attainable for them, and it’s right here close to home.”

INSPIRING STUDENTS

Southern Research STEM outreach
Southern Research scientists and engineers gave high school students from around Alabama a look at their jobs during STEM Day.

Southern Research’s efforts to boost STEM education in Alabama go far beyond a one-day event. The organization’s hiring of Lanier earlier this year is part of a broader goal to inspire more young people across Alabama to pursue careers in science and engineering.

She is working to create hands-on learning experiences that focus on science, technology, engineering and math for students.

“I have the coolest job in the world, and I love it even more every day. I’m developing a STEM outreach program to reach students and teachers across the state. The long-term goal is to increase their interest in STEM and also to make them better at it,” Lanier said.

Greater numbers of students entering STEM careers increases the local pool of talent for future employees. But more importantly, Lanier said, this is a way for Southern Research to give back to local communities.

“Our motivation is that we want to impact these kids in Alabama who are often forgotten, who don’t have as many opportunities as kids in a technology hub would have,” she said. “We want to spark their interest and learning in these fields.”

Jessica Moore, AP physics teacher at Jasper High School, brought eight students, all seniors who are in the midst of making important decisions about college and their course of study.

“I’m happy for them to be exposed to what is offered here at Southern Research, and maybe that will help them narrow down what they want to do in the future,” she said.