Tag: Moving Science

2nd Southeast Energy Storage Symposium focuses on policy, regulation

Southern Research is again hosting the Southeast Energy Storage Symposium, bringing together an array of speakers and panelists to provide attendees with perspectives, benefits, challenges and trends in energy storage, solar policy and regulation.

Now in its second year, the event is begins today at Southern Research’s Oxmoor location on Tom Martin Drive.

The symposium is the only event of its kind in the region and includes keynote speeches and panel discussions featuring experts and professionals from Southern Research, Southern Company, the U.S. Department of Energy (DOE), Tennessee Valley Authority, NextEra, Avista Utilities, Electric Power Research Institute (EPRI) and DOE’s Oak Ridge National Laboratory, Pacific Northwest National Laboratory and Sandia National Laboratory, among many others.

Bert Taube, Ph.D., Energy Storage and Renewables Program Manager at Southern Research’s Energy & Environment division, said the symposium is designed to inform key industry stakeholders about the value of innovative energy storage systems in an effort to accelerate the technology’s development, testing and adoption.

Southern Research energy storage
Steve Baxley, R&D manager at Southern Company Services, is one of the industry panel moderators at Southern Research’s Southeast Energy Storage Symposium, which begins Wednesday, July 17, 2019

Taube said energy storage systems represent a critical technology in the smart electricity grids envisioned for the future because they will support important parts of grid modernization such as the integration of renewables or the coverage of peak demand to help lower costs and cut emissions.

“The symposium provides a collaborative forum for policymakers, regulators, utilities, vendors and technology integrators from the Southeast and across the U.S. Collectively, this group will discuss various aspects of energy storage, including grid interconnection, economic modeling, performance, safety, standards and regulation,” Taube said.

KEY TOPICS

Attendees will participate in a wide breadth of panels and sessions hosted by leaders in the industry.

Keynote presentations will be provided by Alejandro Moreno, DOE’s director of water power technologies; Jeff Burleson, senior vice president of environmental and system planning for Southern Company; and Tim Echols, a commissioner on Georgia’s Public Service Commission.

The symposium will cover topics such as emerging energy storage technologies and its impact on diversification of technologies in the grid infrastructure, regulatory and policy perspectives, project development and finance, economics and valuation, as well as compliance with safety and performance standards.

Panel moderators include:

  • Gary Brinkworth, director of technology and innovation at TVA
  • Richard Simmons, director of energy policy and innovation center at the Georgia Institute of Technology
  • Charlie Vartanian, senior technical advisor at Pacific Northwest National Laboratory
  • Steve Baxley, R&D manager at Southern Company Services
  • Russ Weed, president of CleanTech Strategies
  • Michael Starke, energy storage program manager, Oak Ridge National Laboratory.

EVALUATING TECHNOLOGY

Southern Research energy storage
Southern Research is formally opening its Energy Storage Research Center as an industrywide resource for testing and validating energy storage technologies. The center is located on Southern Research’s Oxmoor campus.

Attendees will be able to see the first grid-scale vanadium-redox flow battery test system from Avalon Battery to be tested and researched at Southern Research. Southern Research is partnering with Southern Company, EPRI, DOE and Oak Ridge National Laboratory to comprehensively evaluate the Avalon technology at the new Energy Storage Research Center, located on Southern Research’s Oxmoor campus.

The test system is expected to be integrated into the Southern Company system’s infrastructure after an extended period of grid-connected performance and safety testing in compliance with an industry-wide developed test manual.

“Flow battery systems have been around for years, but their adoption into mission-critical parts of utility infrastructures has been very limited,” Taube said.

“Flow batteries offer longer-duration energy storage, which makes them a potentially valuable option as a technology choice; however, researchers must continue to evaluate how they can be used to support grid-scale transmission and distribution systems.”

ENERGY STORAGE RESEARCH CENTER

This year’s symposium takes place on the heels of Tuesday’s ribbon-cutting ceremony for the Energy Storage Research Center, Alabama’s first industrywide resource to accelerate the development and deployment of energy storage technologies. The center is designed for third-party innovators from the electric utility industry, academia, government and technology companies to research, develop and demonstrate energy storage solutions.

Symposium attendees will learn more about the technologies and innovations under way at the Energy Storage Research Center and at other laboratories and utilities nationwide.

This year’s event will offer detailed perspectives on energy storage overall and with respect to policy and regulation. It will provide participants the opportunity to explore the various factors that impact current and future energy storage efforts in the Southeast and beyond.

 

Southern Research employees provide $150,000 for internal research projects

Southern Research employees continue to contribute funds to spark research projects that can lead to major discoveries and funding opportunities.

“I’m constantly inspired by the relentless pursuit of discovery that our employees engage in every day. And on top of that, they believe and care so deeply for the mission of Southern Research the they are willing to support it through contributions to the Employee Give Campaign,” said Brynne MacCann, the organization’s development officer.

“Already, the campaign has provided seed funding for significant projects that are on their way to delivering real-world results,” she added. “The campaign perfectly embodies the spirit and mission of our organization.”

Southern Research launched the Employee Give Campaign in June 2016 with the goal of raising $1 million over five years. As of May 2019, nearly $760,000 has been pledged, leaving the Birmingham-based non-profit organization three quarters of the way toward its target.

Funds raised through the Employee Give Campaign provide Southern Research employees the opportunity to pursue novel projects that hold significant promise but may not fit within the organization’s traditional funding structure.

The goal is to drive innovation and collaboration from the bottom up to  foster promising research projects that can attract substantial external funding from sources including the National Institutes of Health (NIH) and other longstanding partners.

FOSTERING INNOVATION

Southern Research
Southern Research employees have provided $150,000 in funding for internal projects through the Employee Give Campaign’s Innovation Grand Challenge.

A key element of the Employee Give Campaign is Southern Research’s Innovation Grand Challenge, awarded annually by peer review.

So far, six scientific projects have received seed funding under the Innovation Grand Challenge, allowing researchers to access significant support from the NIH, the National Cancer Institute, and the National Institute of Allergy and Infectious Diseases.

Winners of Southern Research’s Innovation Grand Challenge for 2018 were:

  • Seth Cohen, senior electrical engineer on the Engineering Systems Development team. Cohen launched a project to develop advanced real-time signaling processing technologies with broad applications in the consumer, aerospace and defense industries.
  • Nathan Fisher, Ph.D., associate director of Bacteriology Laboratory, is leading a team targeting the development of a new treatment for sepsis caused by antibiotic-resistant bacteria. The team is focusing on novel anticancer therapeutics developed by Southern Research as an immune booster to combat the bacterial infection.
  • Susan Schrader, Ph.D., senior scientist in the Infectious Disease Research Laboratory, is working to identify a new therapeutic target that could be key to the discovery and development of new anti-HIV drugs.

Southern Research employees were able to award $150,000 to these projects through the Innovation Grand Challenge.

DRIVING FORCE

The Employee Give Campaign has also generated funds for improvements to Southern Research’s campuses. For 2019, the Wellness Committee is outfitting a workout facility with new equipment for employees on the Southside campus.

Previous projects renovated the Thomas Martin Library on the Southside campus and updated the lobbies at three Southern Research locations.

The Employee Give Campaign is part of a broad-based philanthropic program at Southern Research.

“Philanthropic funding is crucial to the success of early stage scientific research,” MacCann said. “The more we can raise to support our work, the faster we can bring life-saving therapeutics and technologies to those in most need. Our employees are the driving force behind this effort.”

Southern Research’s four operating divisions focus on drug discovery, drug development, engineering, and energy and the environment. Its staff of more than 400 scientists, engineers and researchers work at facilities in Alabama, Georgia, Maryland and Texas.

 

 

3 new members join Southern Research Advisory Board

The Southern Research Advisory Board, comprised of emerging leaders in the Birmingham business community who are committed to enhancing the organization’s mission of scientific and engineering advancement, has added three new members.

Key Foster of McWane Inc., Angele Monconduit of Alabama Power, and Beeland Nielsen of Coca-Cola Bottling Co. UNITED joined the Advisory Board during its first quarter meeting on Feb. 21.

“Southern Research is making great strides in its endeavors today, and we are pleased that these three outstanding leaders have elected to contribute their time and talents to help support the organization’s mission of solving the world’s hardest problems,” said Advisory Board Chairman David Perry, vice president of Corporate Strategy at Protective Life Insurance Co.

KEY FOSTER

Southern Research
Key Foster

Foster joined McWane in 2011 and has responsibility for operating divisions focusing on high-tech companies and commercial real estate investments, as well as corporate development initiatives. Previously, Foster helped lead the turnaround of two public companies, advised Lehman Brothers during its bankruptcy, and executed $13 billion in mergers and acquisitions, financing and real estate transactions.

Foster has held senior management roles in public and private companies and has a successful track record leading early stage growth companies, corporate turnarounds, principal investments and corporate development. He was co-founder of Redmont Hospitality and served in senior roles at Gaylord Entertainment and the Trust Co. of Sterne, Agee & Leach.

Foster received a bachelor’s degree in business administration from Washington and Lee University and an MBA from Vanderbilt University. He holds the Chartered Financial Analyst (CFA) designation.

ANGELE MONCONDUIT

Southern Research
Angele Monconduit

Monconduit serves as the assistant to the executive vice president of External Affairs for Alabama Power. Since 2002, Monconduit has served in a variety of leadership roles responsible for ensuring the safe, reliable, and cost-effective operation and maintenance of the company’s generating power plants.

She is engaged with several civic and charitable organizations, including the Women’s Fund of Birmingham and the National Society of Black Engineers, where she co-hosts an engineering camp for over 200 Birmingham students every summer. She has been recognized by the Engineering Council of Birmingham for her service to the community and is a Distinguished Service Award recipient.

Monconduit graduated from the University of Evansville with a bachelor’s degree in civil engineering.

BEELAND NIELSEN

Southern Research
Beeland Nielsen

As corporate senior director of Commercial Leadership at Coca-Cola Bottling Co. UNITED, Nielsen has responsibility for all commercial leadership and capability functions. He previously served as director of Commercial Leadership-Retail for the company, with responsibility for leading project development and implementation focusing on Go-To-Market processes, strategic route planning, commercial capabilities, and sales force automation.

Prior to joining Coca-Cola UNITED in 2004, he worked for Regions Bank as a management trainee and retail branch manager. He completed a comprehensive management training rotation in Chattanooga, Tennessee, and served as retail sales manager for Coca-Cola UNITED’s Tennessee Valley Division.

Nielsen received a bachelor’s degree in English literature from The University of the South, Sewanne and later completed an MBA at Vanderbilt University.

“The addition of these new members will enhance Southern Research’s relationship with the Birmingham business community,” said Watson Donald, the organization’s senior director of External Affairs. “They will join with the other Advisory Board members to provide us with valuable feedback on our multifaceted activities as they move forward in their own business careers.”

In addition to Perry, existing Advisory Board members are:

  • Alexia Borden, senior vice president and general counsel, Alabama Power
  • Jay Brandrup, principal, Kinetic Communications
  • Deon Gordon, president, TechBirmingham
  • Danny Markstein, managing director, Markstein;
  • Liz Pharo, managing partner, Featheringill Capital
  • Shannon Riley, president and CEO, One Stop Environmental
  • Elizabeth Scribner, analyst, Model Risk Management & Validation,
    Regions Financial Corp.
  • Mitesh Shah, vice president and assistant general counsel, Vulcan Materials Co.

The Southern Research Advisory Board was established in 2015.

Southern Research’s inaugural Change Campaign advances key research programs

Founded in 1941 as a non-profit organization dedicated to improving lives throughout Alabama and beyond, Birmingham-based Southern Research and its scientists and engineers have made significant contributions to multiple fields in its history – including infectious disease, clean air, space exploration and national defense.

But in fall 2018, Southern Research elected to highlight its multi-faceted efforts in neuroscience, cancer research and “green” chemistry through the inaugural Change Campaign, a peer-to-peer fundraiser generating funds to support ongoing research efforts.

“Our passion at Southern Research is driven by hope: hope for a cure, for a cleaner, greener Earth and for lives to be changed – and ultimately saved,” said Southern Research President and CEO Art Tipton, Ph.D. “Donations to the Change Campaign allow us to continue to explore important scientific breakthroughs within high-risk, high-reward endeavors that are many times difficult to fund through traditional government grants.”

Southern Research
Researchers representing the three pillars under the Change Campaign: Amit Goyal (sustainable chemistry), Rebecca Boohaker (cancer research) and Rita Cowell (neuroscience). Image: Mary Margaret Smith)

Fundraising under the Change Campaign, which relied on volunteer “Change Agents,” began in September and lasted for 30 days. The campaign climaxed on Oct. 11 with a community event called the “Evening of Change” on the grounds of Southern Research’s downtown Birmingham campus.

The one-month initiative ultimately raised more than $200,000 while simultaneously building awareness of the organization’s groundbreaking work in select fields.

“Southern Research’s mission is simple – make the world a better place. Our teams are passionately developing innovative technologies that positively impact real-world problems. We cannot progress our efforts – or be successful – without the support of our partners and the community,” said Southern Research Development Officer Brynne MacCann.

The Change Campaign’s showcase of the following three pillars of scientific inquiry under way at Southern Research included:

  • Neuroscience: This department is devoted to discovering effective central nervous system therapies to prevent, treat or cure neurological diseases and mental health disorders. Investigators are exploring the underlying mechanisms of neuronal cell death and dysfunction in Parkinson’s, Alzheimer’s, Huntington’s, ALS and schizophrenia.
  • Cancer Research: Since Southern Research began its cancer research program in 1946, its scientists have saved countless lives through the development of effective chemotherapy techniques, the discovery of seven FDA-approved anticancer drugs and the testing of many medicines now on the market. Today, researchers are evaluating new treatment targets, investigating how to activate the immune system to kill tumor cells, and developing potential new anticancer drugs.
  • Green Chemistry: The goal of Southern Research’s work in sustainable chemistry is to develop environmentally friendly and cost-efficient methods for making valuable chemicals or products from materials essentially considered to be waste. Researchers have devised ways to convert waste biomass sugars into the building block of carbon fiber, as well as to transform harmful carbon dioxide into chemicals needed to make everyday products.

    Southern Research
    Southern Research President and CEO Art Tipton speaks at the Change Campaign’s ‘Evening of Change’ event. (Image: Mary Margaret Smith)

ATTACKING REAL-WORLD PROBLEMS

Southern Research’s staff of nearly 400 workers is structured along four operating divisions: drug discovery, drug development, engineering and energy and environment. Besides the Birmingham research complex, it operates laboratories and offices in Maryland, Georgia and Texas.

The organization has and will continue to pursue entrepreneurial and collaborative initiatives to develop and maintain a pipeline of intellectual property and innovative technologies that positively impact real-world problems.

In keeping with this commitment, Southern Research has also worked closely with BioAlabama in 2018, helping the trade organization bring more visibility to Alabama’s growing biotech ecosystem and the incredible work being done in the state. The industry’s impact on the state has been calculated at more than $7 billion annually.

Southern Research Recognizes 2018 President’s Award and Excellence Awards Winners

Southern Research honored winners of its 2018 Employee Excellence Awards in a program last week.

The winners include 24 individuals and five teams across technical and administrative staff and represent Southern Research’s diverse divisions and departments. All have shown a deep commitment to Southern Research’s mission, its sponsors, and their colleagues.

Their accomplishments supported Southern Research in a wide range of efforts during 2018, from advancing science and technology to making the organization a safer, more efficient, and more productive workplace.

This year, President and CEO Art Tipton, Ph.D., recognized Judy Britt for her contributions and dedication to Southern Research with The President’s Award.

SR President and CEO Art Tipton recognized Judy Britt for her contributions and dedication to Southern Research with The President’s Award.

Britt currently serves as contracts manager, where her deep experience with both government and commercial proposals and contracts has been invaluable to SR teams. In this role, she manages some of SR’s largest and most complicated agreements. She freely shares her wealth of knowledge with her colleagues, and she is never too busy to answer a question. The impact of this institutional knowledge is felt across the organization.

“Over a 30-year career at Southern Research, Judy Britt has set a shining example of customer service and dedication,” Tipton said. “Most notably, Judy’s work and dedication to Southern Research’s contracts efforts has furthered the organizational mission to solve the world’s hardest problems, particularly in the areas of space flight, national defense, energy, the environment, and new therapeutics to treat various diseases.”

As part of her award, Britt was presented with the Thomas Wesley Martin Medal. A limited number of these coins were made in 1961 as a gift to the board of trustees to show appreciation for a select number of scientists who have made phenomenal achievements in their respective fields.

Receiving Excellence Awards for their work in 2018 were:

Jamie Bell: In his new leadership role within the Drug Development in vivo group, Bell has gone above and beyond to improve the management of the animal husbandry department and train new staff members, resulting in a vast improvement of the facilities and processes.

Donghui Bao, Ph.D.: In just four years, Bao has exponentially grown the capabilities and services of the bioanalytical laboratory within Drug Discovery’s Chemistry Department, providing the drug discovery program with the vital data necessary to support its extensive number of research programs for diseases such as diabetes, Parkinson’s, multiple myeloma, and more.

Tommy Brooks: As SR’s dedicated staff electrician, Brooks manages crucial, multifaceted electrical systems and projects for all SR facilities. He was recognized for his outstanding customer service, relentless dedication, and on-time completion of projects.

Pam Burn: Burn was recognized for her devotion to encouraging cooperation with the environmental health and safety principles across all of SR. She works diligently to provide an effective communication path and safe work environment for all employees.

Jennifer Carl: Carl has been incredibly responsive and proactive in helping facilitate transactions between the Drug Development business development team and the contracts team. Her broad, specialized knowledge of the business combined with her professionalism has helped expedite a routinely lengthy and complicated process.

Steve Clark: In just two years, Clark has managed to greatly improve efficiency in contracts processes and procedures for the mechanics research component of SR Engineering. By engaging team members to better understand SR’s key customers, contract requirements, and the overall business, he has taken customer relations to a higher level.

Seth Cohen: As an engineer on Engineering’s system development team, Cohen has developed, proposed, and received multiple project funding. In just one year, his innovative applications of chaos theory to practical problems have earned him five awards for novel technology development.

Ron Dainton: Dainton directed the demolition and redesign efforts for a major renovation project at SR’s Frederick, Maryland, infectious disease research facility. His oversight of day-to-day construction activities helped ensure all facility research endeavors continued with minimal disruption.

Steve Gallagher: Within his role on the IT support team, Gallagher has exemplified SR’s core values in his daily interactions with all SR staff. He has consistently demonstrated respectful, open communication and dedicated support across all teams, departments and cultures.

Lynae Hanks, Ph.D.: As the lead for Drug Discovery’s proposal writing efforts, Hanks has played an integral role in helping elevate the quality and volume of the division’s proposals. Her contributions and dedication to the process have contributed significantly to the division’s ability to achieve its short- and long-term goals.

Keith Hendershot: As a team member in SR’s Environmental Analytical Lab, Hendershot operates large scale pilot units and water treatment systems for some of SR’s biggest clients. His dedication and knowledge have ensured projects run seamlessly and that customers are continually satisfied.

Ame Johnsey: Johnsey was recognized for her exemplary service and support of the entire organization through her management of the CEO’s schedule and facilitating events, activities and notable visitors. She goes above and beyond in her role with a positive attitude and dedication.

Shelby Massey: As a team member in Engineering’s hypersonic structures group, Massey has adapted to accommodate large volumes of challenging work while at the same time encouraging and supporting team members across the division. Her dedication to excellence has helped boost the success of the hypersonic structures team’s efforts.

Synthia Mayfield: Mayfield was recognized for her significant contributions to Drug Development’s pathology group, particularly in providing support to the team during times of increased workloads and challenging circumstances. Alongside her main role, she took on additional responsibilities and developed new skills to help manage scheduling and resources for the team.

Matthew Merrell, Ph.D.: As a senior scientist and study director in Drug Development, Merrell manages complex studies for a range of customers. This year, he handled two particularly challenging studies and managed to exceed customer expectations and deliver on time results.

Lutfiya Miller, Ph.D.: In 2018, Miller spearheaded an effort within Drug Development’s toxicology program to develop neurobehavioral assessment capabilities. Her contributions have increased revenue for the program and will lead to more opportunities for the toxicology team to serve one of its largest and oldest clients, the National Toxicology Program.

Bhavesh Patel: Patel was recognized for his technical skills as a vital member of Engineering’s materials characterization group and his success in winning and performing work in the commercial space sector. He has also played an instrumental role in the restructuring of Engineering’s thermal lab to improve efficiency.

Lillie Ryans: Ryans has demonstrated a commitment to her craft through diligence, intelligence, and a thorough understanding of the complex contracting world that exists for SR and its customers. Day in and day out she leads by example and helps technical groups achieve success through the critical role she plays for the organization.

Jadid Samad, Ph.D.: In addition to his team oriented approach and dedication, Samad was recognized for the key role he has played in bringing in significant, new DOE research contracts for E&E’s sustainable chemistry and catalysis group. He has also filed three patents for new technologies, and one was issued within just one year.

Denora Shanks: Shanks, a team member in accounts payable, has demonstrated excellence in her interactions with and support of Engineering’s mechanics group, especially in regard to that group’s high-volume workload. Her role requires her to interact with both internal and external clients, and she has gone out of her way to display professionalism and to share her knowledge.

Krupa Subramanian: A biologist in Drug Development, Subramanian has conducted innovative work in the HIV research space by developing a modified quantitative viral outgrowth assay (QVOA) that is superior to the gold-standard method for HIV reservoir quantification. The new assay is being well received by government clients including DAIDS-NIAID of NIH.

Samuel Tanner: Tanner, a chemist in Drug Discovery, has excelled in his new role as manager of the group’s compound collection by increasing efficiency of the delivery of chemical samples and by revamping the collection’s commercial inventory. He has helped fix software issues to help improve accuracy and reduce costs.

Megan Tidwell: Tidwell was recognized for her proactive and results-oriented approach to trouble-shooting accounting issues, particularly in support of the contracts group. She recently stepped into a new role and has drastically improved contracts processes thanks to her creative solutions and positive approach to challenges.

Gabrielle Williams: In her role as lead security guard, Williams was tasked with creating upgraded ID badges for the high-security Engineering facility. She managed to accomplish the upgrade in record time.

The Drug Development Anatomic Pathology Group: This team is responsible for the execution of the necropsy and histology work in Drug Development. This year, they have collaborated to improve procedures, cut costs, and upgrade work standards and quality. Additionally, they have established a successful mentoring and training program to help all team members succeed.

The Engineering Asbestos Program Team: Team members Tony Sanford and Richard Cooley were tasked with a particularly challenging project – characterizing hazardous asbestos containing material. They met the challenge, working long hours in a demanding environment to complete the testing needed.

The Engineering Machine Shop Modernization Team: Kenneth Nicholson and Joshua Washburn were instrumental in helping the shop upgrade its equipment and capabilities in a short amount of time. Their technical knowledge, passion, and interpersonal skills led to a complex upgrade of the entirety of the shop’s tools and equipment.

The Dapivirine Study Group: These Drug Development team members were recognized for their exceptional team work and commitment to excellence for a study on the HIV prevention drug Dapivirine. Their collaborative design of a communication strategy, consistently outstanding work performance, and technical innovation were all keys to formulating a study design, generating extensive data, and interpreting the data within a tight timeline. Their successful delivery of study outcomes exceeded the customer’s expectations, which turned into additional business from this customer. Team members include Zhaohui Cai, Jiayi Wei, Christy Raney, Hayley Madeira, Junzhong Peng, Carol Lackman-Smith, Beth Snyder, and Amy Sands.

The Proposal Process Team: Debbie Dille, Steve Clark, and Christopher Tanner worked as a team to improve the process of managing large proposals, which has increased efficiency across the board. The team implemented a new system that is more precise and flexible, allowing for better communication between technical and business personnel in order to increase response time.

Southern Research completes $13 million renovation of Frederick facility

FREDERICK, Maryland – Southern Research marked the completion of a $13 million renovation project at its Frederick Infectious Disease Research Center with a ribbon-cutting ceremony today attended by local leaders, state officials and research sponsors.

The project, launched after the 48,000-square-foot facility sustained damage during a torrential rain storm that struck Frederick three years ago, adds flexibility to the center’s operations and prepares it for future growth.

“Southern Research’s facility in Frederick has played an important role in advances in treatment of infectious diseases over nearly three decades, and this additional investment underscores our commitment to the groundbreaking infectious disease research being conducted here,” said Art Tipton, Ph.D, the Birmingham-based organization’s CEO and president.

Southern Research
Southern Research employees mark the completion of a $13 million rebuilding project at the Frederick Infectious Disease Research Center.

“I want to acknowledge the dedication of all of our Frederick employees during this rebuild in continued commitment to carry out important research for our customers,” he added. “The rebuild would not have been possible without the hard work of many SR employees on our facilities team both in Frederick and Birmingham.”

Infectious disease researchers at the Frederick center primarily focus on antiviral work and carry out activities such as drug and vaccine discovery and development for commercial and government clients. The center has 50 employees.

“We’ve helped pharmaceutical companies get many of their drug candidates into the clinic for trials, and the vast majority of FDA-approved antiretroviral drugs for HIV were tested in this facility,” said Roger Ptak, senior director of Infectious Disease Research for Southern Research in Frederick.

“We’ve also done a lot of significant work in developing animal models for dengue and Zika for potential vaccines against those viruses,” he added. “We have conducted pre-clinical testing on many vaccine and drug candidates here and provided support for lots of programs.”

ANTIVIRAL SCREENING

The Frederick facility, which opened in 1991, was soon handling Southern Research’s large-scale anti-HIV/AIDS screening efforts, and it made significant contributions to treatments against the disease. Today, there are more than two dozen FDA-approved AIDS antiretroviral drugs, often used in therapeutic combinations, and Southern Research was heavily involved in helping many of them get to market.

While the infectious disease research in the early days in Frederick focused on anti-HIV efforts, the center’s antiviral screening capabilities rapidly expanded to include many other viruses. These have included influenza (including the H5N1 avian flu), hepatitis B and C, dengue, anthrax, poliovirus, SARS, and Zika.

Southern Research
Southern Research CEO Art Tipton, left, poses with Ben Wu, deputy secretary and chief operating officer of the Maryland Department of Commerce, at the Frederick ribbon-cutting ceremony.

Southern Research scientists in Frederick have also developed primate models to evaluate vaccines against AIDS and anthrax, as well as other models for influenza and infections caused by monkeypox, a virus similar to smallpox.

The Maryland lab also conducts a high volume of antiviral screens against a variety of viruses for pharmaceutical companies, biotech firms, small labs, academic groups, and startups.

Rick Weldon, the president and CEO of the Frederick County Chamber of Commerce who has served in a variety of community roles, said the Southern Research lab and its employees have long been valued partners in the region.

“As the head of local United Way several years ago, I saw the passion of charity and generosity of Southern Research workers, from leadership to the lab bench to the administrative employees,” Weldon said. “Now as the Chamber CEO, I’m both grateful for the significant investment and excited to see what breakthroughs emerge from the work of the Frederick-based Southern Research team.”

STORM DAMAGE

The intense storm that pounded Frederick County on Sept. 29, 2015, dumped 5 inches of rain on the city, causing major flooding that affected local schools and wrecked the YMCA building.

Southern Research’s Frederick facility was hit hard by what was described at the time as a “100-year storm.”

Ptak said the heavy rains caused part of the roof in the rear of the structure to collapse. As part of the repair project, the back corner of the building was demolished and completely rebuilt.

“The rebuild allowed us to reconfigure and optimize the space, and we now have space to grow,” he said.

Birmingham-based HOAR Construction handled the construction project.


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Looking toward a greener tomorrow: Change Agent Elizabeth Scribner

Elizabeth Scribner thought she knew what was going on at Southern Research. Her father’s solar company helped Southern Research install solar panels at its Solar Research Center, and she’s on the board of a local foundation that has donated money to SR. But last year, when she was invited to serve on SR’s Advisory Board, she realized how much she had yet to learn.

“I didn’t know the half of what Southern Research is doing, as far as scientific research and engineering go,” she said. She was amazed to hear about the telescopes SR designed to photograph the eclipse from NASA’s high-altitude research aircraft and the advances in cancer research she hadn’t known about.

“What really grabbed me was when Dr. Amit Goyal came to speak about some of his green energy research,” Scribner said. “I was amazed to hear that he’s developed technology that turns sugar into acrylonitrile, which is used in cars and planes, and I had to smile when I heard about Legos,” said the mother of three. Learning that SR could replace a product that relied on oil refinery with one that used renewable resources, “I got very excited about that,” she said. “Knowing that, and getting a little more energized about everything Southern Research is doing, inspired me to be a Change Agent.”

SR wasn’t her first introduction to green science. “Before I was a mathematician, or a mom, or a wife, I was an environmentalist,” Scribner said. “As an undergraduate at Princeton, I had a minor in environmental studies. And I started learning about all the damage we’ve done to our planet. But on the other side, I also started learning about all the promise that science holds in terms of helping solve those problems.”

Scribner appreciates the platform the Change Campaign provides to talk about Southern Research. “When I tell people, they’re amazed,” she said. “They say, ‘I had no idea this is here in Birmingham.’ And here Southern Research is creating scientific change to improve the world, but they’re also creating jobs and attracting amazing intellectual talent to our city.” She sees great potential in the acrylonitrile technology to create jobs in poorer regions of Alabama. “If we could use this technology to not only improve the condition of our planet but also improve the economic situation in our state, that would be amazing,” she said.

“I’ve got a lot going on. My life is pretty busy. But I feel like it’s a gift for me to be able to volunteer for a group like Southern Research,” Scribner said. “It helps me to step above the day-to-day ‘What am I going to fix for dinner? Oh, no, we’re out of diapers’ and see the bigger picture. We’re not going to be here forever. But my kids’ kids will have kids who will be here a hundred years from now. It’s important to me that they have the ability to eat fresh food, breathe clean air and drink clean water. There’s a lot of work to be done. And here in Birmingham, I feel like we have someone to advocate for that.”

Nurturing bright ideas: Change Agent Key Foster

Key Foster wasn’t unaware of Southern Research’s decades long focus on cancer and the numerous life-saving drugs to SR’s credit. But that wasn’t the main reason he chose to support cancer research as part of the Change Campaign. “Cancer is very meaningful to me,” he said. “My wife is a breast cancer survivor, and my father lost his battle with kidney cancer in May. It’s a very personal issue.”

He found out that it was a very personal issue for a lot of people. “Cancer is a topic that, if you intersect with it, it’s a big deal,” Foster said. “And it’s shocking how many people have, either personally or through their families, intersected with it.” When he opened up to others in the community about his experiences with cancer, he was surprised at the number of people who were inspired to share not only their money but their own personal stories. “Hearing all that, it’s not surprising that people are so willing to participate,” he said.

One thing Foster appreciated was the significance of the funds he was raising through the Change Campaign—funds that would go directly to research scientists just down the street who had the potential to move mountains, if given the right resources. The money will support earlier-stage, higher-risk research that hasn’t progressed enough to qualify for federal grants. “It’s like venture capital for scientists,” he said.

“It gives ideas a chance,” Foster said. “I assume there’s a good number of really bright ideas that never make it to the surface, never get a chance to come to fruition or evolve into something, because of that funding gap. This money gives these scientists a chance to incubate those ideas and get them to the point where they can get those government grants to continue the research that could one day birth new drugs and therapies for cancer.”

“It can truly move the needle with smaller amounts of money. It just makes the whole thing make sense,” Foster said. “It would be thrilling to contribute, even in our small way, in support of a major breakthrough by one of these brilliant scientists.”

Because those ideas are being created and nurtured here in Birmingham, Foster was able to meet—and be amazed by—the research scientists who would be turning those donations into discoveries. He was particularly inspired by the work of oncology researcher Rebecca Boohaker, Ph.D., much of whose research focuses on immunotherapy.

“These are therapies that enable the immune system to recognize, target and eliminate cancer cells wherever they are in the body,” he said. “This is potentially a universal answer to cancer.” Boohaker’s research could one day mean happy endings for all the stories he heard during the Change Campaign, “and I get to know the real players who have dedicated their careers and lives to solving these really tough problems,” he said.

An Eye on the Mind: Change Agent David Powell

When, during the leadup to the Change Campaign, David Powell was asked if he knew anything about what Southern Research does, his answer was no. “I’ve driven past it a million times and had no idea what was really going on here,” he said. When he was invited to tour the campus instead of just driving past, he was amazed at the discoveries being made right in the middle of Birmingham.

SR’s focus on neurodegenerative disease, in particular, stood out sharply to him because of the harsh introduction he’d had to the subject the previous year. Last December, Powell’s mother died of ovarian cancer. But her cancer diagnosis came nine months after her Alzheimer’s diagnosis—and he was shocked to learn that she saw the cancer as a blessing. “Her mother had a protracted battle with Alzheimer’s,” he said. “And to my mom, cancer seemed like the better option.” SR’s research, he realized, had the potential to make the disease less terrifying.

“Southern Research is a part of Birmingham that needs to be told,” he said. “There weren’t enough people spreading that message.”

Powell was happy to do that, sharing his enthusiasm not just with old friends in Birmingham but with new friends made on dozens of business trips. “By the time you get to dinner, people are tired of talking about business,” he said. “You’re looking for interesting things to talk about.”

He even has a surefire opening line. “I’ll say, ‘Tell me about your city. What’s going on here?’ And that usually invites the question, ‘Well, what about where you’re from? What’s going on there?’” What’s going on in Birmingham is groundbreaking discovery at Southern Research.

That kind of awareness is crucial, he said, when working with diseases like Alzheimer’s and Parkinson’s. “Unfortunately, I think the neurodegenerative things are something people see and just say, ‘Aw, that’s sad,’ as opposed to, ‘Aw, that’s something we should do something about,’” he said. The diseases are lengthy and devastating for both the patient and family, “but they aren’t necessarily as attractive for investment. Or they’ve been forgotten while we spend money on something that seems more current.” Or, he said, less insurmountable.

“Insurmountable” isn’t a concept Powell believes in. He prefers the tech industry concept of “zero to one”—“Something didn’t exist, then it exists,” he said. He wants to see that kind of energy directed toward medical discovery. “How can we take a disease that was incurable and make it curable? How do we take something that was an impossible problem to solve and then solve that problem?”

Powell noted that in 1900, the two leading causes of death were flu and gastrointestinal distress. “We’d laugh,” he said. “‘People in 1900 died of flu and diarrhea? Who dies like that?’ I’d like to think that in 2018, we could flash forward 40 years and people would say, ‘People died of ovarian cancer? Who dies of ovarian cancer? Who dies of Alzheimer’s? That’s ridiculous!’”

Southern Research taps Stacey Kelpke to head AIMTech initiative

Southern Research announced today that Stacey S. Kelpke, Ph.D., an experienced biomedical/bioengineering researcher, has been named program manager of its medical device technologies initiative, AIMTech.

In her new role, Kelpke oversees a program that aims to accelerate the development of early-stage medical device technologies as potential commercial products through prototyping, market validation, and other forms of assistance.

“The AIMTech initiative harnesses the power of Birmingham’s world-class medical knowledge, precision engineering and manufacturing expertise to move ideas toward the medical device marketplace,” said Mark J. Suto, Ph.D., vice president of Drug Discovery at Southern Research.

“Stacey has a strong background in biomedical engineering, and she possesses the talents to move AIMTech forward on its important mission.”

Southern Research medical devices
Stacey Kelpke is program manager for Southern Research’s AIMTech medical technology development initiative.

Southern Research formed AIMTech in 2014 to combine the research and discovery capabilities of the Birmingham-based non-profit organization’s scientists and engineers with entrepreneurs and clinicians. The program’s goal is to facilitate the development of new medical devices to improve healthcare in the U.S. and around the world.

“We’re really focusing on medical technologies, which encompasses medical devices but also big data, artificial intelligence, robotics and personal management apps,” Kelpke said.

“We’re exploring where Southern Research fits into this space and how we can actually make an impact for the patient. That is what this is all about – impacting patient care.”

AIMTech PIPELINE

Kelpke said AIMTech is well positioned to help establish the Birmingham area as a center for medical device business formation by capitalizing on the region’s rich heritage in manufacturing and its dynamic healthcare sector.

Southern Research AIMTech
A unique treadmill called the ResistX was developed as part of the AIMTech program.

She said AIMTech operates on a solid foundation, with projects in its pipeline poised to move forward. One of those is ResistX, a unique force-induced treadmill that allows people recovering from neurological or physical disorders to exercise. The device, developed with a team from the University of Alabama at Birmingham (UAB), debuted in 2017.

Kelpke arrives at AIMTech at a time when global demand for medical device technologies is expanding at a compound annual growth rate projected to top 5 percent over the next few years. The U.S. remains the world’s largest single medical device market, valued at around $156 billion, or nearly 40 percent of the global market in 2017, according to data from the U.S. Commerce Department.

Kelpke previously worked at UAB, most recently serving as licensing manager for medical devices for the university’s Harbert Institute for Innovation and Entrepreneurship. Between 2013 and 2018, she negotiated license agreements with biotech and medical companies that generated more than $1.5 million in revenue.

Prior to that, she was an instructor and researcher at UAB, where she secured funding for four R&D projects and authored 11 peer-reviewed papers.

Kelpke earned a master’s degree and a doctorate in biomedical engineering from UAB, as well as a bachelor’s degree in mechanical engineering from Auburn University.


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