Tag: Moving Science

Wall Street Journal: GeoVax Labs Shares Rise 12% After Licensing Deal for Cancer Treatment

Posted on September 30, 2021

By Chris Wack

GeoVax Labs Inc. shares were up 12% to $4.68 after the company said it entered into an assignment and license agreement with PNP Therapeutics Inc., granting GeoVax exclusive rights to develop and commercialize Gedeptin, a novel patented product for the treatment of solid tumors.

The biotechnology company said the license provides exclusive worldwide rights to key intellectual property, including Gedeptin patents, know-how, regulatory filings, clinical materials and trademarks.

The patent portfolio covering Gedeptin was originally licensed from the University of Alabama at Birmingham and Southern Research Institute by PNP. Under the License, GeoVax will become the successor to PNP under its license agreement with UAB/SRI.

Detailed financial terms of the transaction weren’t disclosed, but include a combination of upfront payments, milestone fees, and royalties on net sales.

A Phase 1/2 trial, evaluating the safety and efficacy of repeat cycles of Gedeptin therapy in patients with recurrent head and neck squamous cell carcinoma, with tumors accessible for injection and no curable treatment options, is currently enrolling. The initial stage of the study is being funded by the U.S. Food and Drug Administration pursuant to its Orphan Products Clinical Trials Grants Program. The FDA also has granted Gedeptin orphan drug status for the intra-tumoral treatment of anatomically accessible oral and pharyngeal cancers, including cancers of the lip, tongue, gum, floor of mouth, salivary gland and other oral cavities.

Write to Chris Wack at chris.wack@wsj.com

Birmingham Business Journal: Josh Carpenter looks to boost IP and job growth at Southern Research

Posted on August 23, 2021

A familiar name took over as president and CEO of Southern Research earlier this year.

Josh Carpenter, the former director of innovation and economic opportunity for the city of Birmingham, took the reins at Southern Research on June 1.

After getting acclimated, Carpenter has established several goals to guide the nonprofit.

He said he wants to draw on his experience with job creation in the public sector and apply it to the scientists at Southern Research to create more spinoff companies, leading to more economic development.

“When I think job creation at Southern Research, I think of it in a couple of buckets. Obviously we have 400 employees, so we have direct jobs that we create. We have indirect jobs that we create in our supply chain, whether it’s collaborative research with UAB or working to provide contract-based research …,” Carpenter said. “So the idea is that we will work and our scientists will create in-house discoveries that can then be translated from ideas to innovation and from innovation to economic opportunity and economic growth.”

Another priority for Carpenter is to make improvements and additions to the Southern Research campus in Southside. He said he first wants to renovate the spaces and modernize the lab equipment to make room for new technologies, data and lab information management systems. This is to make sure the data and samples that are created can be analyzed and collected more easily, resulting in services being delivered more quickly.

Carpenter is looking to create a number of facilities as well. He noted Southern Research has not built a new building on its campus in Southside this century, and the new facilities will boost partnerships with UAB in key areas.

“Our major areas of focus are definitely going to be immunotherapy, immuno-oncology and emerging infectious diseases,” he said. “What we really believe is that if we do all that right, we can become a center for pandemic preparedness in Birmingham and Alabama, and that will enable us to not only serve our residents and ultimately serve patients more effectively in one of the country’s most diverse populations, but it will also help us grow jobs in our community.”

Carpenter is also committed to growing revenue from intellectual property by creating a cleaner process for patent development and then surrounding those patents with new companies and new venture capital.

“We want to be a platform into the private sector. We’re sort of one step into academia and one step in the private sector. We want to help translate those technologies and commercialize those technologies,” he said.

“That means not just growing but it’s also a means of attracting the right talent. We want people who want to come into our doors and say, ‘Hey, I really want to push on patents, and my own goals are to create companies from the discoveries that I make.’”

https://www.bizjournals.com/birmingham/news/2021/08/19/carpenter-southern-research-goals.html

Southern Research employee honored by national LGBTQ+ science organization

Posted on August 2, 2021

A national organization devoted to LGBTQ+ individuals in scientific or technical careers is honoring a longtime Southern Research employee with a new scholarship specifically geared to individuals in biosciences.

LaVinia Ray, manager of the Anatomic Pathology and Central Repository Groups at Southern Research, received Out to Innovate’s inaugural Amy A. Ross Scholarship in Bioscience on July 31. The $2,000 award was established to recognize those who enhance LGBTQ+ visibility, diversity and inclusion in biosciences.

Ray said she is honored to receive the scholarship, which will support her work toward a Bachelor’s of Science degree in Interdisciplinary Studies at the University of West Alabama.

“As a woman scientist and a member of the LGBTQ+ community, I have encountered many barriers to my growth and development,” she said. “However, one thing has held strong – my commitment to making the path an easier one for those who follow in my footsteps.”

Ray has worked for Southern Research for 20 years, and said she has been fortunate to work at an institution that has long valued and celebrated diversity. Specifically, she said, Southern Research was among the early companies to provide insurance coverage for same-sex spouses. “I am so proud to work for Southern Research and pleased with its stance on equality for all,” she said.

Josh Carpenter, president and CEO of Southern Research, said Southern Research is equally proud of Ray.

“LaVinia is widely recognized not only for her technical expertise, but also for her ability to mentor, support and inspire those on her team,” Carpenter said. “She is a leader in every sense of the word, and she is an asset to Southern Research. We are proud to see that others recognize her accomplishments as much as we do.”

Out to Innovate, formerly known as the National Organization of Gay and Lesbian Scientists and Technical Professionals, is made up of professionals who work in science, engineering and other technical fields. The organization works to empower LGBTQ+ individuals in STEM by providing education, advocacy, professional development, networking and peer support.

The group provides scholarships for LGBTQ+ students to pursue degrees in STEM fields, with the goal of promoting academic excellence and increased visibility of LGBTQ+ students in STEM fields. This is the first year that the organization has awarded the Amy A. Ross Scholarship in Bioscience.

Southern Research neuroscience lab wins grant for Parkinson’s, ALS research

Posted on July 14, 2021

A Southern Research neuroscience lab has received new federal grants totaling almost $3.9 million to advance its study of Parkinson’s Disease and other neurological diseases.

The grants from the National Institute of Neurological Disorders and Stroke include $3.3 million to study Parkinson’s and $594,000 for research related to frontotemporal dementia, a disease that is similar to Amyotrophic Lateral Sclerosis, or ALS.

Both grants will support a lab led by Rita Cowell, Ph.D., fellow and chair of the Department of Neuroscience in Southern Research’s Drug Discovery Division.

“These grants are a reflection of the excellence and dedication of our neuroscience team,” said Josh Carpenter, president and CEO at Southern Research. “They work every day to fight diseases that have devastated the lives of so many families. They are an asset to Southern Research and to our community.”

Cowell’s lab has worked for 15 years to study why brain cells die and lead to neurological diseases that cause an ongoing and often devastating decline in a person’s physical and mental abilities.

“If we can understand why these cells die, then we may be able to find drugs to interfere with that and stop the progression of these diseases,” she said.

For Parkinson’s, the lab received a five-year grant to advance its research on a molecule that may keep brain cells alive. The length and amount of the federal grant reflects the strong preliminary data that Southern Research has compiled in past research supported by the Michael J. Fox Foundation for Parkinson’s Research, the Southern Research Change Campaign and the Meyer Foundation.

The second grant will support two years of additional exploratory research about how neurons stop functioning in frontotemporal dementia and ALS, and will be led by Cowell and Kazutoshi Nakazawa, also at Southern Research.

Cowell is particularly proud that this exploratory grant builds on initial work at Southern Research that was supported by the Alabama Power Foundation. “That investment from our own community created the base that is allowing us to go to the next level,” Cowell said.

Southern Research is leading the research on both grants. Co-investigators on these grants are located at UAB, Virginia Tech and the University of Michigan.

Birmingham’s Southern Research appoints CEO, EVP

Posted on May 14, 2021

Southern Research, the groundbreaking scientific discovery and research institution headquartered in Birmingham, on Thursday announced that its board of directors has appointed Josh Carpenter, Ph.D., as its new president and CEO, and Allen Bolton as its new executive vice president for Strategy and Finance.

Both appointments are effective June 1.

Founded in the Magic City in 1941, Southern Research is an independent, non-profit scientific research organization where more than 400 scientists and engineers work across three divisions: Life Sciences, Engineering, and Energy & Environment. Southern Research has attracted national research partnerships with leading industries in the fields of pharmaceuticals, biotechnology, defense, aerospace, the environment and energy.

“Josh and Allen are forward-thinking leaders who are ready to chart a bold new course for Southern Research,” stated University of Alabama at Birmingham President Ray L. Watts, who is chairman of the Southern Research board of directors. “They have the full support of the Board as they begin to lead an amazing team of scientists, engineers and innovators who are working to solve problems and change the world for the better.”

Southern Research generates over $150 million in annual economic impact and supports more than 1,000 Alabama jobs.

“The work of Southern Research results in life-changing advancements and innovative solutions,” said Southern Research board member Mark Crosswhite, who also serves as the chairman, president and CEO of Alabama Power Company. “Josh and Allen’s vision and expertise will play an important role in leading this institution forward as a continued center of excellence.”

Carpenter most recently served as director of Innovation and Economic Opportunity for the City of Birmingham, where he led the City’s efforts in workforce development, COVID recovery and business expansion. Previously, he served as the director of External Affairs at UAB. He earned his doctorate in political economy from the University of Oxford where he studied on a Rhodes Scholarship.

“I am truly honored to take the helm of Southern Research and lead this incredible team that is finding solutions to improve people’s lives around the world. Southern Research has had 80 successful years, but I know the best is yet to come,” commented Carpenter.

Bolton most recently served as senior vice president for Finance and Administration at UAB, where he was also a member of the board for Southern Research. He was previously an executive in finance and strategy at the Medical College of Wisconsin, and was senior associate dean for Administration and Finance at the UAB School of Medicine as well as executive administrator at the Comprehensive Cancer Center, the largest research center in the University of Alabama System.

“Discoveries made at Southern Research have provided breakthroughs in cancer research, pushed the boundaries of science and saved lives. I am grateful for this opportunity to work alongside dedicated and talented people who have an unmatched passion for science and discovery,” concluded Bolton.

https://yellowhammernews.com/birminghams-southern-research-appoints-ceo-evp/

Birmingham’s Southern Research under new leadership

Posted on May 14, 2021

Josh Carpenter, PhD, has been appointed president and CEO and Allen Bolton executive vice president for strategy and finance at Birmingham-based Southern Research.

The scientific discovery and research institution employs more than 400 scientists and engineers.

“Josh and Allen are forward-thinking leaders who are ready to chart a bold new course for the company,” said University of Alabama at Birmingham President Ray Watts, chairman of the Southern Research board of directors and interim CEO since the departure of Art Tipton in 2019.

“They have the full support of the board as they begin to lead an amazing team of scientists, engineers and innovators who are working to solve problems and change the world for the better.”

Carpenter served as director of innovation and economic

opportunity for the City of Birmingham before coming to Southern Research. Previously, he was director of external affairs at UAB. He holds a doctorate in political economy from the University of Oxford, where he was a Rhodes Scholar.

“I am truly honored to take the helm of Southern Research and lead this incredible team that is finding solutions to improve people’s lives around the world,” Carpenter said.

Bolton most recently served as senior vice president for

finance and administration at UAB.
Founded in Birmingham in 1941, Southern Research is an independent, nonprofit scientific

research organization where scientists and engineers work across three divisions: life sciences, engineering and energy & environment.

https://businessalabama.com/birminghams-southern-research-under-new-leadership/

Southern Research Appoints Josh Carpenter as President and CEO and Allen Bolton as Executive VP for Strategy and Finance

Posted on May 13, 2021

Two prominent Birmingham leaders have been named to leadership posts at Southern Research – the scientific discovery and research institution headquartered on Birmingham’s Southside.

Josh Carpenter has been named president and CEO, and Allen Bolton has been named executive vice president for strategy and finance. They begin the new roles on June 1.

They’ll be taking the reins at an organization with vast potential for shaping the future of Birmingham’s economy and its innovation ecosystem.

Carpenter, a Rhodes Scholar, most recently served as director of innovation and economic opportunity for the city of Birmingham. He previously worked at UAB.

Bolton most recently was senior vice president for finance and administration at UAB where he also served on the board of Southern Research.

“I couldn’t be more enthusiastic about what’s in front of us because of the people who are there,” Carpenter said.

In addition to the expertise of the people and the legacy of Southern Research, Carpenter said he was attracted to the role because of the organization’s potential to transform the region’s economy.

Historically, he said Birmingham has been home to many islands of innovation. One of his goals is to create a better through-line to connect those pockets of R&D excellence in the community and raise their collective impact.

“Southern Research, perhaps better than any other organization, is specifically geared toward playing the role of that translational bridge – translating ideas to innovation and economic opportunity,” Carpenter said. “If we can create the storefront to access those immense capabilities, we can present ourselves as the next frontier market in biotech.”

Carpenter said Birmingham is well-positioned for growth in life sciences, precision medicine and related fields, and he said Southern Research, with expertise in those fields and others, can play a critical role in that innovation economy.

With the way the medical sector is trending, Carpenter sees a growing need for the type of capability expertise that can be found on the campus of Southern Research, which has 400 employees.

He’s also excited about the role the organization can play in building the local innovation ecosystem – an effort with vast implications for Birmingham’s economy.

There have been numerous examples of successful biotech companies that have originated from research conducted in Birmingham but ultimately moved elsewhere. One of his goals at Southern Research is to help build an environment that keeps those companies – and the jobs they create – in metro Birmingham.

“Southern Research is at it’s finest when the halls are brimming with first-rate intellect that come up with a novel discovery that becomes a commercial enterprise and creates jobs right here in Birmingham,” he said.

Carpenter said there will be a focus on having a deeper and more profound relationship with UAB, which is located adjacent to Southern Research’s campus.

“We have not tapped the potential of working to integrate our approach,” he said.

Carpenter also said a priority will be adapting Southern Research’s business model to capitalize on the opportunities at hand. What that will entail is likely to become more clear with a strategic plan that could be released later this year to coincide with Southern Research’s 80th anniversary.

He said he’s happy to have a veteran leader like Bolton joining him at Southern Research.

“No one has better experience navigating not just the UAB ecosystem, but a labyrinth of medical systems,” Carpenter said. “He’s going to be a really effective arbiter of our strategic and financial interests.”

https://www.bizjournals.com/birmingham/news/2021/05/13/new-leaders-take-the-reins-at-southern-research.html

Southern Research selects new president and CEO

Posted on May 13, 2021

Birmingham’s Southern Research announced today that Josh Carpenter will be its new president and CEO, effective June 1.

Allen Bolton will also serve as its new executive vice president for strategy and finance.

Carpenter recently served as the City of Birmingham’s director of innovation and economic opportunity, where he led the city’s efforts in workforce development, COVID recovery and business expansion. He will lead the independent, non-profit scientific research organization which employs more than 400 engineers and scientists.

UAB President Ray Watts, who chairs the Southern Research Board of Directors, said Carpenter and Bolton are “forward-thinking leaders who are ready to chart a bold new course for Southern Research.” Alabama Power President and CEO Mark Crosswhite, a board member, said the two men’s “vision and expertise will play an important role in leading this institution forward as a continued center of excellence.”

Carpenter also previously served as UAB’s director of external affairs and earned a doctorate in political economy from the University of Oxford, where he studied on a Rhodes Scholarship.

“I am truly honored to take the helm of Southern Research and lead this incredible team that is finding solutions to improve people’s lives around the world,” he said. “Southern Research has had 80 successful years, but I know the best is yet to come.”

Bolton most recently served as UAB’s senior vice president for finance and administration and served as a Southern Research board member. He was also executive administrator at the Comprehensive Cancer Center, the largest research center in the University of Alabama System.

“Discoveries made at Southern Research have provided breakthroughs in cancer research, pushed the boundaries of science and saved lives,” Bolton said. “I am grateful for this opportunity to work alongside dedicated and talented people who have an unmatched passion for science and discovery.”

Southern Research generates more than $150 million in annual economic impact and supports more than 1,000 Alabama jobs.

https://www.al.com/news/birmingham/2021/05/southern-research-selects-new-president-and-ceo.html

Histotechnology Professionals Day at Southern Research

Posted on March 10, 2021

In honor of Women’s History Month and Histotechnology Professionals Day, Southern Research wants to take a moment to recognize our team of histotechnologists and their team leader, LaVinia Ray. She was deemed by the National Society of Histotechnology to be the 2020 Histotechnologist of the Year and the 2016 Advanced Laboratory Technician of the Year.

LaVinia was able to receive a proclamation from the Governor of Alabama to name this week Histotechnology Professionals Week and from the Mayor of Birmingham to mark March 10^th Histotechnology Professionals Day in Birmingham. She constantly lifts up her team members and enjoys bringing her team deeper into the field by helping them get ready to sit for their HT American Society of Clinical Pathologists certification exam. We’re proud to have her and her team with us at Southern Research.

Histotechnology is a science that centers around the microscopic detection of abnormal tissue that helps in the diagnosis and treatment of diseases. This knowledge and understanding of composition is what allows pathologists to give a clinical diagnosis and treatment plan based off of differences in appearances from healthy tissue and the abnormality.

Our highly skilled technicians are HT American Society of Clinical Pathologists (ASCP) certified or certification eligible experts in their field. Our full-service laboratory team has established a long track record of proven success and high quality work. Southern Research provides necropsy and histology services tailored to the unique needs of research and veterinary clients. If you want to know more about the customized services that our qualified team can offer, check out our page on Anatomic and Clinical Pathology.

Southern Research makes key leadership announcements

Posted on November 12, 2020

Southern Research has named Michael Catalano and Mark Suto, Ph.D., chief operating officer and vice president for Life Sciences, respectively. Previously, Catalano served as interim COO, and Suto was VP for Drug Discovery and interim VP for Drug Development.

University of Alabama at Birmingham President Ray L. Watts serves as Southern Research interim CEO and chairman.

“Michael and Mark have provided forward-thinking and effective leadership during this critical time of notable progress for SR and collaboration with UAB,” Watts said. “Solidifying these positions of leadership will enable SR to build on its strong trajectory and positive momentum.”

Catalano joined SR in 2017 as general counsel and assumed the interim COO role in 2018. As permanent COO, he will continue to manage the day-to-day operations of SR.

“I am honored to continue to serve in this role and humbled every day to work with our incredible teams at SR,” Catalano said. “I am proud of all we continue to accomplish together and excited about our future.”

Since joining SR in 2011, Suto has developed multiple research collaborations spanning a diverse array of diseases. In his new role, he will build on ongoing efforts to unite Drug Discovery and Drug Development to optimize growth in SR’s Life Sciences portfolio and impact.

“We have made great strides in evolving drug discovery and drug development in recent years as we ensure SR is well-positioned as a modern life sciences organization,” Suto said. “We have a bright future, and I am excited for this opportunity.”

Both promotions are effective immediately.

Prior to SR, Catalano was general counsel and privacy officer at Influence Health; chief operating officer, corporate secretary and general counsel for SilverStaff Inc.; vice president of finance for Caesars Entertainment Inc.; and senior development counsel for pharmacy health care provider CVS Caremark.

Suto has more than 35 years of experience working in several large pharmaceutical companies, as well as smaller biotech and venture-backed organizations. He has led multidisciplinary programs that resulted in the identification of clinical candidates in several therapeutic areas.

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