We are capable of evaluating the efficacy, safety, and pharmacokinetic properties of your potential therapeutic compounds targeting prion disease. We offer a comprehensive suite of preclinical prion disease services tailored to address the unique challenges posed by these diseases, encompassing every stage of the research process:
Anti-Prion Compound Screening and Optimization: We utilize a range of in vitro screening assays to identify promising anti-prion compounds and optimize their efficacy and selectivity.
Pharmacokinetic and Pharmacodynamic (PK/PD) Studies: We determine the absorption, distribution, metabolism, and excretion (ADME) properties of anti-prion compounds, providing valuable insights into their pharmacokinetic profiles and pharmacodynamic effects.
Regulatory Support and IND Preparation: We guide you through the intricate regulatory landscape, ensuring compliance with FDA guidelines and facilitating the preparation of Investigational New Drug (IND) applications.